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Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response

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Figure

Figure 1: Constitutive activation of IL-6 signaling and phenotype characterization. A
Table 2: Tumor formation in athymic nude mice
Figure 2: Challenge with oxidative stress and consequences of higher ROS levels. A. Colony formation induced by oxidative stress
Figure 3: Mechanisms of ROS-induced transformation. A. Levels of P21. RNA was extracted after 8 h treatment and relative expression levels were determined by qPCR with a basket housekeeper as internal control and mock-transfected FH-hTERT as calibrator (ex

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