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Development of a Rapid High Throughput Method for High Resolution Melting Analysis for Routine Detection and Genotyping of Noroviruses

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Figure

FIG. 1. Principle of high-resolution amplicon melting-curve analy-sis to produce fluorescence difference plot curves
FIG. 2. Genotyping of noroviruses within a 380-bp fragment usinghigh-resolution amplicon melting-curve analysis
FIG. 3. Alignment of the nucleotide sequences and difference plots of four different clones of the GII/4 plasmid samples
TABLE 2. Comparative study of HRM with RT-PCR, sequencing,and real-time PCRa

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