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Adaptive evolution that requires multiple spontaneous mutations. I. Mutations involving an insertion sequence.

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Figure

FIGURE 1.-Structure inserted of the bgl operon in strain ~ 3 4 2 .  IS103 is into the bglF gene
FIGURE 2.-Time  course  of excision bglR+ Conkey salicin medium.  Strain Sal' papillae  formation  on Mac- XSWl requires  only  a bglRo + mutation  to  form Salf papillae,  strain 101 1A requires  only of IS103 from within bglF to  form Sal+ papillae,  whi
TABLE 1 Mutation rates
FIGURE 3,"Excision  of papillae on MacConkey salicin medium).  Lane  12: resed,  transferred MacConkey salicin medium)
+3

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