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Histone H3K4 and H3K36 Methylation Independently Recruit the NuA3 Histone Acetyltransferase in Saccharomyces cerevisiae

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Figure 1 NuA3 is primarily bound to midgene regions of actively transcribed genes. (A) The average sequence coverage relative to 4701 +1 nucle-enrichment by quartiles of sense NET-seq (Churchman and Weissman 2011) signal for genes longer than 1500 bp
Figure 2 NuA3 is associated with H3K4me3, H3K4me2, H3K4me1, and H3K36me3 nucleosomes genome wide
Figure 3 H3K4 and H3K36 methylation are necessary for Sas3 binding to active genes through Pdp3 and Yng1, respectively
Figure 4 Sas3 occupancy does not dictate histone H3K23 acetylation. (A) The average enrichment relative to 4264 +1 nucleosomes for Sas3 andsynthetic media lacking histidine, and incubated at 30position and by (C) Sas3 or (D) Gcn5 (Xue-FranzénSerial dilutio

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