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AUTONOMIC NERVOUS SYSTEM

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Somatic efferent and ANS

Somatic Efferent

Control

External environment

single somatic efferent neuron

Acetlycholine

…is over skeletal muscles.

This division of the PNS responds to some change in the external environment.

Extends from the CNS to the effector (skeletal muscle) … is the NT released at the synapse (motor endplate.)

(3)

Autonomic nervous system

(visceral efferent)

Regulates visceral activities

No conscious control

Stable internal environment

Organs of the thoracic and abdominal regions; sweat and sebaceous glands, etc.

…over visceral activities.

(4)

Autonomic nervous system

Regulated by centers in

2 efferent neurons

One from CNS to ganglion

One to visceral effector

Acetlycholine (ACh) or norepinephrine (Ne)

CNS

Brain stem and cord

preganglionic postganglionic

Are the NTs released at the synapses.

preganglionic postganglionic ganglion

(5)

Structure of the ANS

Visceral efferent neurons organized into

Nerves (neurons)

Ganglia

Plexuses

Entirely motor

Pre- or postganglionic nerves.

Where the pre- or postganglionic neurons form a synapse; this is where the postganglionic soma is located.

Tangles of visceral efferent nerves.

(6)

1) Efferent neurons

preganglionic

Soma in brain or cord Myelinated axons

Synapses with postganglionic neuron

CNS

(7)

Postganglionic

autonomic ganglia Unmyelinated axons Synapses with effector

1) Efferent neurons

CNS

Somas are located within autonomic ganglia or target organs are found with postganglionic neurons

(8)

Sympathetic

thoracolumbar

helps body respond to stress

1) Efferent neurons

CNS

division of the ANS has its preganglionic somas in the... regions of the cord

This division of the ANS is called the “fight or flight’ division. If the body is under some threat or stress, the sympathetic stimulation goes up.

This causes an increase in heart and respiration rate, sweating, blood flow to the CNS and muscles.

This causes a decrease blood flow to some visceral organs, such as the intestines and the kidneys.

(9)

Parasympatheic

craniosacral

active under normal conditions

1) Efferent neurons

CNS

division of the ANS has its preganglionic somas in the... regions of the cord

This division of the ANS is called the “rest and repose” division. The parasympathetic division is stimulated under normal or resting conditions, when you want to cover from stress; build up reserves and maintain the body.

This causes a decrease in heart and respiration rate, sweating, blood flow to the CNS and muscles.

This causes an increase blood flow to some visceral organs, such as the intestines and the kidneys.

(10)

Dual innervation

The heart, each visceral organ and gland is innervated by both the sympathetic and parasympathetic divisions of the ANS.

Although each effector is under the control of both divisions, they are not simultaneously stimulated by both.

Which division predominates at any given time is determined by the demands on the body at that time.

(11)

2) Autonomic ganglia

a) sympatheic trunk or chain ganglia (

paravertebral or lateral ganglia

)

Sympathetic division

Preganglionic fibers are short

Located close and lateral to the spinal cord. Stimulate primarily...

(12)

2) Autonomic ganglia

b) prevertebral ganglia (collateral ganglia)

Sympathetic division

Preganglionic fibers are short

Located anterior to the spinal cord. Stimulate primarily...

(13)

b) prevertebral

ganglia (collateral

ganglia)

Largest

Celiac

Superior mesenteric ganglia

inferior mesenteric ganglia

Some examples of prevertebral ganglia

Postganglionic fibers from this ganglion innervate organs of the abdomen; liver, gallbladder, stomach, pancreas, spleen.

Innervate the small intestine and part of the large.

Innervate most of the large intestine, kidney, bladder and reproductive organs.

(14)

2) Autonomic ganglia

c) terminal ganglia

Parasympathetic division

Preganglionic fibers are very long

Located within target visceral organs. Stimulate primarily...

(15)

3) Plexuses

Interlaced networks

Solar plexus or Celiac

plexus

Similar to the plexuses of the somatic

efferent PNS.

Tangles of visceral efferent nerve fibers.

Postgangionic fibers from the celiac ganglion pass through here.

(16)

Physiology of the ANS

Autonomic fibers release NT at synapse

Cholinergic

Adrenergic

…fibers release Ach at the synapse.

The preganglionic fibers of the sympathetic division are cholinergic. Ach is released to bind to the postsynaptic (postganglionic) neuron. …fibers release norepinephrine (NE) at the synapse.

(17)

Responses

Catechol-O-methyl transferase 

NE tends to stimulate the effectors.

This enzyme, found in the synaptic gap, breaks down NE.

It has a similar function as acetylcholinesterase, but works at a slower rate.

As a result some NE tends to diffuse out of the synapse into the surrounding tissues, where it may exert an effect.

So the effects of sympathetic stimulation are more wide spread and last longer the parasympathetic stimulation.

(18)
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Responses

Parasympathetic:

 

Both pre- and postganglionic fibers are cholinergic.

As Ach is rapidly broken down by acetylcholinesterase, it does not have a chance to diffuse from the synapse.

(20)

Visceral Autonomic Reflexes

smooth muscle

cardiac muscle

gland secretion

…similar to somatic reflexes. Target organs are...

Such as digestive system, vessels, reproductive.etc. Heart

Salivary, sweat, etc.

receptor

afferent neuron association neuron

visceral efferent preganglionic neuron 

visceral efferent postganglionic neuron

visceral effector 

(21)

Visceral sensations

conscious sensations

Control by higher centers

Hypothalamus

Cerebral cortex

Visceral sensations reach the conscious

levels of the mind if the a voluntary action is required to deal with the sensation; as in

urination or defecation.

For example; if hypothalamus determines that the the water content of the blood is too low, it will send signals to the higher brain centers to provide a sensation of thirst.

The cerebrum will respond to the thirst

sensation by stimulating drinking behaviors; a voluntary action.

References

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