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Specific inhibition of one DNMT1-including complex influences tumor initiation and progression

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Figure

Figure 1 Specific disruption of DNMT1/protein-x interactions. (A) Representation of DNMT1 with its functional domain (nuclear localizationsignal: NLS, BAH1 and two domains, domain CXXC and its catalytic domain) and with amino acid domains of interaction wi
Figure 2 Impact of specific inhibition of DNMT1/protein-x interaction. (A) Tumorigenicity test of Astro#40 cells transfected with plasmidsencoding for indicated peptides or pre-treated with procainamide

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