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Reactivation of mutant p53 by capsaicin, the major constituent of peppers

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Figure

Fig. 1 CPS induces cell death in mutp53-expressing cells in a p53-dependent manner.16 and 24 h
Fig. 2 p53 interference reduces the CPS-induced cell death inThe percentage of p53 reduction was measured by densitometry andplotted in the right panel.dead cells was scored by trypan blue staining
Fig. 3 CPS induces mutp53 protein degradation.Tunel assay. Equal amount of total cell extracts was analysed by western immunoblotting with anti-p53 and anti-p62 antibodies
Fig. 4 CPS restores wtp53 activities in mutp53-carrying cells.analysis.of the total chromatin (Input) was included as control
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