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Microtubule-Associated Protein Mdp3 Promotes Breast Cancer Growth and Metastasis

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Figure

Figure 1. Mdp3 is highly expressed in human breast cancer tissues and cell lines. (A and B) Immunohistochemical staining of Mdp3 in breast cancer tissues (A) and adjacent tissues (B), with negative (-), low (+), medium (++), and high (+++) expression
Figure 2. Mdp3 promotes the proliferation of breast cancer cells. (A) Immunoblot analysis of Mdp3 and control or Mdp3 for 48 hours
Figure 3. Mdp3 stimulates the motility of breast cancer cells. (A) Immunoblot analysis of Mdp3 and performed as in B, and the extent of wound closure was analyzed
Figure 4. Mdp3 increases breast cancer growth and metastasis in mice. (A) MDA-MB-231 cells were transfected with control or Mdp3 siRNAs, and the transiently-silenced cells were injected subcutaneously into the right flanks of female athymic nude mice (7 mic
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