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SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome

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Figure

Figure 1 Probing interactions between SH2 domains and physiological peptide ligands at a systems level
Table 1 Literature confirmed interactions 39 array-positive interactions were experimentally verified or confirmpreviously reported interactions while 23 array-negative interactions empirically suggest a threshold corresponding toa KD of approximately 5 to 10 μM for this data set
Table 1 Literature confirmed interactions 39 array-positive interactions were experimentally verified or confirmpreviously reported interactions while 23 array-negative interactions empirically suggest a threshold corresponding toa KD of approximately 5 to 10 μM for this data set (Continued)
Table 2 Measured affinity values
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