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Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus

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Figure

Table 1. Peripheral blood B cell subsets of healthy donors (n ≥ 25), and quiescent (n ≥ 20) and active (n = 10) SLE patients
Figure 1. Decreased CD19 and CD21 expression on SLE B cells. (A) CD19, CD21, CD81, and CD225 mean fluorescence intensity (MFI) ratios of CD19+ B cells from quiescent (n = 22) and active (n = 10) systemic lupus erythematosus (SLE) patients compared with hea
Figure 2. CD19 downregulation appeared concomitantly with CD21 expression on maturing B cells
Figure 3. Impaired TLR9 responses in SLE B cells. Frequency of CD86donors (HDs; stimulation of B cells with polyclonal F(ab+CD69+ (A) and TACI+CD25+ (B) in gated CD20+CD27– naive B cells from healthy n = 19) or systemic lupus erythematosus (SLE) patients w
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