3
rdInternational Symposium on Metabolic Programming and Stress
(September 25-28, 2013) Morretes/PR, Brazil
______________________________________________________________________
3 rd International SMPS - Program
Wednesday 25
th, Afternoon – (Session 1: 15h:00min – 16h:35min ) Welcome – (15h:00min – 15h:15min)
Paulo C.F. Mathias, PhD
Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR – Brazil
_____________________________________________________________________________________
Chair – Elaine C. Vieira, PhD Lecture – (15h:15min – 15h:55min)
Revisiting the fetal origin of adult diseases (FOAD) hypothesis: recent findings and future directions
Didier Vieau, PhD
University of Lille 1, Lille – France ([email protected])
Short Communication – (15h:55min – 16h:05min)
Perinatal high-fat programming induces parasympathetic nervous system hyperactivity and affects pancreatic beta cell function in weanling rats
Luiz F. Barella, PhD
Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR – Brazil
Short Communication – (16h:05min – 16h:15min)
Changes in muscarinic receptor subtypes composition in pancreatic islets from obese rats Rosiane A. Miranda, MSc
Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR – Brazil
Discussion – (16h:15min – 16h:35min)
_____________________________________________________________________________________
Coffee-break – ( 16h:35min – 16h:45min )
Wednesday 25
th, Afternoon – (Session 2: 16h:45min – 18h:45min ) Chair – Patrícia C. Lisboa, PhD
Full Communication – (16h:45min – 17h:25min)
Involvement of pancreatic α-cells in the glucocorticoids-induced glucose dyshomeostasis Alex Rafacho, PhD
Laboratory of Investigation in Chronic Diseases, Department of Physiological Sciences, Federal University of Santa Catarina, Florianópolis/SC – Brazil
Short Communication – (17h:25min – 17h:35min)
Stressed pattern by maternal low-protein diet programs pancreatic β-cell function to resist dexamethasone disturbances in adult rat offspring
Júlio C. de Oliveira, PhD
Department of Physiological Sciences, Roberto Alcântara Gomes Biology Institute, State University of Rio de Janeiro, Rio de Janeiro/RJ – Brazil & Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR – Brazil
Short Communication – (17h:35min – 17h:45min)
Hypothalamus-pituitary-adrenal axis disruption changes pancreatic islets muscarinic receptors composition in programming-obese rats
Audrei Pavanello
Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá – Brazil
Full Communication – (17h:45min – 18h:25min)
Early life protein malnutrition metabolic programming of insulin resistance in diet-induced obesity (DIO)
Claudio C. Zoppi, PhD
Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas/SP – Brazil ([email protected])
Discussion – (18h:25min – 18h:45min)
_____________________________________________________________________________________
Dinner – (18h:45min)
Thursday 26
th, Morning – (Session 1; 09h:00min – 10h:20min ) Chair – Latifa Abdennebi-Najar, PhD
Full Communication – (09h:00min – 09h:40min)
Cardiovascular, renal and metabolic sequelae in offspring exposed in utero to a maternal diet high in saturated fat.
James A. Armitage, PhD
School of Medicine (Optometry), Deakin University; Waurn Ponds 3228, Victoria – Australia ([email protected])
Short Communication – (09h:40min – 09h:50min)
The glucocorticoids and their effects on clock genes expressions from pineal glands.
Rafaela E.A. Dantas
Departamento de Morfologia, Universidade Federal de Sergipe, São Cristóvão/SE – Brasil.
Short Communication – (09h:50min – 10h:00min)
Fetal programming in cardiovascular and metabolic diseases Paula H.O. Lima, PhD
Laboratório de Investigação Molecular em Cardiologia, Instituto Dante Pazzanese de Cardiologia, Universidade de São Paulo (USP), São Paulo/SP – Brasil
Discussion – (10h:00min – 10h:20min)
_____________________________________________________________________________________
Coffee-break – ( 10h:20min – 10h:30min )
Thursday 26
th, Morning – (Session 2; 10h:30min – 12h:30min ) Chair – Alex C. Manhães, PhD
Full Communication – (10h:30min – 11h:10min)
Leptin: new insights into IUGR pathology Latifa Abdennebi-Najar, PhD
Unité de Recherche Expression des Gènes et Régulation Epigénétique par l'Aliment, Institut Polytechnique LaSalle, Beauvais – France
Short Communication – (11h:10min – 11h:20min)
Short-term exercise prevents autonomic dysfunction related to obesity, but not cardiovascular changes induced by high-fat diet in rats
Kesia Palma-Rigo, PhD
Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR – Brazil
Short Communication – (11h:20min – 11h:30min)
Insulin secretion and action are altered by in vitro amino-acid restriction: possible role of sirtuins
Sarah Rickli
Department of Structural and Functional Biology, University of Campinas (UNIICAMP), Campinas/SP – Brazil ([email protected])
Full Communication – (11h:30min – 12h:10min)
Neonatal environmental stress on neuronal changes and behavior in rats Aldo B. Lucion, PhD
Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde (ICBS); Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS – Brazil
Discussion – (12h:10min – 12h:30min)
_____________________________________________________________________________________
Lunch – ( 12h:30min – 14h:00min )
Thursday 26
th, Afternoon – (Session 1; 14h:00min – 16h:00min ) Chair – Aldo B. Lucion, PhD
Full Communication – (14h:00min – 14h:40min)
Metabolic flexibility in adipose tissue and skeletal muscle of MGS-obesity model is positively modified by chronic aerobic exercise
Luiz C. Fernandes, PhD
Federal University of Parana, Curitiba/PR – Brazil ([email protected])
Short Communication – (14h:40min – 14h:50min)
A role for chronic exercise on glucose metabolism of skeletal muscle from undernourished obese mice
Nayara C. Leite, MSc
Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas/SP – Brazil ([email protected])
Short Communication – (14h:50min – 15h:00min)
Characterization of MSG-induced obesity as a new model for polycystic ovary syndrome Renato S. Gaspar
Department of Physiological Science, Federal University of Maranhao, São Luis/MA – Brazil ([email protected])
Full Communication – (15h:00min – 15h:40min)
Evolutional characterization of nonalcoholic steatohepatitis in monosodium L-glutamate-induced obese mice
Antônio M.A. Paes, PhD
Department of Physiological Science, Federal University of Maranhao, São Luis/MA – Brazil ([email protected])
Discussion – (15h:40min – 16h:00min)
_____________________________________________________________________________________
Coffee-break – ( 16h:00min – 16h:10min )
Thursday 26
th, Afternoon – (Session 2; 16h:10min – 18h:10min ) Chair – Deborah M. Sloboda, PhD
Full Communication – (16h:10min – 16h:50min)
Breaking the programming fate: functional food (flaxseeds) and drugs (metformin and buscopan) Paulo C.F. Mathias, PhD
Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR – Brazil
Discussion – (16h:50min – 17h:00min)
_____________________________________________________________________________________
Conference – (17h:00min – 17h:50min)
The importance of a Brazilian DOHaD Society : perspectives and possibilities
Chair – Paulo C.F. Mathias, PhD
Chair of the Conference for the Brazilian Society of DOHaD
Deborah M. Sloboda, PhD
Member of the International DOHaD Society
Latifa Abdennebi-Najar, PhD
Treasurer of the French Society of DOHaD
_____________________________________________________________________________________
Work-shop – (17h:50min – 18h:20min)
Designing and manufacturing PowerLab/MacLab data acquisition systems for life science ADInstruments Company
(http://www.adinstruments.com)
Discussion – (18h:20min – 18h:30min)
_____________________________________________________________________________________
Dinner – (18h:30min)
Friday 27
th, Morning – (Session 1; 09h:00min – 10h:20min ) Chair – Antônio M.A. Paes, PhD
Full Communication – (09h:00min – 09h:40min)
Metabolic compromise after early life nutritional adversity Deborah M. Sloboda, PhD
Faculty of Health and Sciences, McMaster University, Hamilton/ON – Canada ([email protected])
Short Communication – (09h:40min – 09h:50min)
Neonatal serotonin reuptake inhibition promotes reduces metabolic indicators in adult rats Manuella L.D. Barros
Departament of Physiotherapy, Federal University of Pernambuco (UFPE), Recife/PE – Brazil ([email protected])
Short Communication – (09h:50min – 10h:00min)
Endocrine and metabolic function are altered in a model of anxiety disorder Felippe Mousovich-Neto, MSc
1Laboratório de Fisiologia Endócrina Doris Rosenthal (LFEDR), Instituto de Biofísica Carlos Chagas Filho (IBCCF), Universidade Federal do Rio de Janeiro – (UFRJ), Rio de Janeiro/RJ – Brasil.
Discussion – (10h:00min – 10h:20min)
_____________________________________________________________________________________
Coffee-break – ( 10h:20min – 10h:30min )
Friday 27
th, Morning – (Session 2; 10h:30min – 12h:30min ) Chair – Elena Zambrano, PhD
Full Communication – (10h:30min – 11h:10min)
Differences in behavioral outcomes at adulthood between models of early weaning in rats Alex C. Manhães, PhD
Departamento de Ciências Fisiológicas, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro/RJ – Brasil
Short Communication – (11h:10min – 11h:20min)
Lactational serotonin reuptake inhibition increased hypothalamic expression of 5-HT
2Creceptor in adulthood rats
Lígia C.M. Galindo, PhD
Postgraduate Nutrition, Department of Anatomy, Universidade Federal de Pernambuco (UFPE), Recife/PE – Brasil ([email protected])
Short Communication – (11h:20min – 11h:30min)
Extraction, expansion and characterization of stem cells from fat tissue of individuals with metabolic syndrome
Daniana M. Bronoski
Biological and Health Science Multidisciplinary Laboratory, State University of Ponta Grossa, Ponta Grossa/PR – Brazil.
Full Communication – (11h:30min – 12h:10min)
Undernutrition and stress Ana L. Sawaya, PhD
Universidade Federal de São Paulo, São Paulo/SP – Brasil ([email protected])
Discussion – (12h:10min – 12h:30min)
_____________________________________________________________________________________
Lunch – ( 12h:30min – 14h:00min )
Friday 27
th, Afternoon – (Session 1; 14h:00min – 16h:00min ) Chair – Alex Rafacho, PhD
Full Communication – (14h:00min – 14h:40min)
Insulin and insulin-like growth factor 1 signaling as a fine control on insulin synthesis, and their secretion from different animal models.
Anderson C. Marçal, PhD
Departamento de Morfologia, Universidade Federal de Sergipe, São Cristóvão/SE – Brasil.
Short Communication – (14h:40min – 14h:50min)
Stress and melanoma: an in vitro evaluation of melanin production and tumor growth.
Rebecca S.M. Stival
Biological and Health Science Multidisciplinary Laboratory, State University of Ponta Grossa, Ponta Grossa/PR – Brazil.
Short Communication – (14h:50min – 15h:00min)
Metabolic programming by small litters impairs the VO
2maxperformance of rats during the exercise program
Gabriel S. Fabricio
Department of Physical Education, State University of Maringa, Maringá/PR – Brazil ([email protected])
Full Communication – (15h:00min – 15h:40min)
Diet and exercise interventions before and in pregnancy prevent adverse programming offspring outcomes of obese mothers
Elena Zambrano, PhD
Department of Reproductive Biology, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Mexico City – Mexico
Discussion – (15h:40min – 16h:00min)
_____________________________________________________________________________________
Coffee-break – ( 16h:00min – 16h:10min )
Friday 27
th, Afternoon – (Session 2; 16h:10min – 18h:10min ) Chair – Ana L. Sawaya, PhD
Full Communication – (16h:10min – 16h:50min)
Effects of early adrenaldemedullation on fat accumulation in lean and obese trained rats Ana E. Andreazzi, PhD
Laboratory of Endocrine Neurophysiology and Physical Exercise; Department of Physiology; Federal University of Juiz de Fora, Juiz de Fora/MG – Brazil
Short Communication – (16h:50min – 17h:00min)
Duodenal-jejunal bypass improves insulin secretion stimulated by Cch and PMA in islets from obese rats
Mariana C. Mendes
Laboratório de Fisiologia Endócrina e Metabolismo, Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel/PR – Brasil ([email protected])
Short Communication – (17h:00min – 17h:10min)
Effects of maternal separation on eating behavior and stress reactivity in rats Julliet A. de Souza
Department of Nutrition, Health Centre (CCS) & Department of Anatomy, Centre of Biological Sciences, Federal University of Pernambuco, Recife/PE – Brazil
Full Communication – (17h:10min – 17h:50min)
Melatonin prevents insulin resistance and mitochondrial dysfunction induced by palmitate in rat primary skeletal muscle cells.
Elaine C. Vieira, PhD
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Universidad Miguel Hernandez de Elche, Elche – Spain
Discussion – (17h:50min – 18h:10min)
Entertainment – (18:15min)
A piece of music with the APAE Orchestra from Ponta Grossa – ( in the Main Square of Morretes )
_____________________________________________________________________________________
Saturday 28
th, Morning – (Final session; 09h:00min – 12h:00min ) Conference – (09h:00min – 11h:00min)
Conference for setting up collaborations Chair – Paulo C.F. Mathias, PhD
The organizing members of the International Symposium on Metabolic Programming and Stress invites everyone to this session to tie new collaboration works and to discuss the organization for the 4
thInternational Symposium on Metabolic Programming and Stress.
_____________________________________________________________________________________
Coffee-break – ( 11h:00min – 11h:15min )
_____________________________________________________________________________________
Final discussion – (11h:15min – 11h:45min)
Talking about the election and chosen for the next place where the 4
thInternational Symposium on Metabolic Programming and Stress could be held.
_____________________________________________________________________________________
Closing remarks – (11h:45min – 12h:00min)
Marcos R.R. da Silva, MD, PhD
State University of Ponta Grossa, Ponta Grossa/PR – Brazil ([email protected])