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Original Article Low molecular weight heparin prevents lipopolysaccharide induced-hippocampus-dependent cognitive impairments in mice

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Figure

Figure 1. Schematic timeline of the experimental procedure, dose-response of LMWH on fear conditioning test in mice, and effects of LMWH treatment on the survival rate within 7 days after LPS administration
Figure 2. Sepsis-induced cognitive impairments were reversed by LMWH treatment. A, B. No significant difference was observed in the total distance traveled in the open field test on day 7 after LPS administration among the four groups
Figure 3. Sepsis-induced enhanced neuroninflammation and oxidative stress were attenuated by LMWH treatment
Figure 4. Representative western blotting and quantitative analysis of TLR-4, NF-κB p65, iNOS, Cox2, occludin, HMGB1, and BDNF in the hippocampus
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