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Original Article Galunisertib, a TGF-β receptor (TβR)-I inhibitor, suppresses growth and invasion of an anaplastic thyroid cancer 8505C cell in vitro and in vivo

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Academic year: 2020

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Figure

Figure 1. Effects of galunisertib on TGF-β signaling expression. 8505C cells was treated with 10 μM galunisertib for 2-24 hrs
Figure 2. Galunisertib treatment inhibits invasion of human 8505C cells in Matrigel-coated invasion chambers
Figure 3. Effects of Galunisertib on 8505C cell growth and apoptosis. 8505C cells were treated with Galunisertib (10 μmol/L) for 3 days
Figure 4. Effects of galunisertib on tumor growth and metastasis in vivo. A. 8505C ATC cells (5 × 106) were inoculat-ed subcutaneously into the right flank of 4- to 6-week-old female athymic nude (nu/nu) mice

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