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MSK1 regulates transcriptional induction of Arc/Arg3 1 in response to neurotrophins

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Figure

Table 1. qPCR primer sequences.
Fig. 1. MSK1 promotes Arc/Arg3.1 mRNA induction downstream of BDNF. (A) Wild-type cortical neuronal cultures were pretreated asindicated for 1 h with 2 lM PD184352, 5 lM SB203580, 10 lM Kn-93 or 10 lM PI103
Fig. 2. MSK1 regulates the induction of the Arc/Arg3.1 promoter. (A) Wild-type or MSK1 D194A KI cortical neurons were stimulated with2–50 ng�mL�1 BDNF for 60 min or left unstimulated
Fig. 3. Arc/Arg3.1 mRNA induction by BDNF is independent ofCREB phosphorylation. (A) Wild-type, MSK1/2 knockout or CREBS133AKIcorticalneuronalcultureswerestimulatedwith50 ng�mL�1 BDNF for 1 h and the induction of nur77 mRNAdetermined by qPCR
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