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Reverse signaling by semaphorin 6A regulates cellular aggregation and neuronal morphology

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Figure

Fig 1. Sema6A exerts constitutive and PlxnA2-dependent cell-autonomous functions. (Sema6A-K393D and treated with AP or PlxnA2-EC;(Sema6A-K393D;expressed as meanA-F) NIH3T3cells expressing GFP alone (A and B), myc-Sema6A-FL (Sema6A; B and E), or myc-Sema6A-
Fig 2. Forward and reverse Sema6A-PlxnA2 interactions have different effects on the migration ofcerebellar neurons
Fig 3. Sema6A signaling reduces the axonal length of granular neurons. (layers;ANOVA followed by Bonferroni multiple comparison test
Fig 4. PlxnA2 interacts with Sema6A in cis and in trans. (A) Scheme summarising Sema6A-AP bindings
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