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Characterising cell membrane heterogeneity through analysis of particle trajectories

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Figure

Figure 1.2: Top-down view of the “fences and pickets” plasma membranemodel. Compartmentalised (or “hop”) diffusion is caused by membrane cytoskeleton“fences” and anchored protein “pickets”
Figure 2.1: Fit of a two-state diffusion model without measurement noise tothe probability of being in the low diffusion state
Figure 2.3: Fit of a two-state diffusion model with measurement noise toing probabilities per frame, (D) corresponding samples (12 chains) foran LFA-1 trajectory (PMA+Cal-I treatment)
Figure 2.4: Model selection between approximate one-state and two-state dif-whisker plot of log Bayes factors by treatment, trajectories with log Bayes factor outside1.5 times IQR are plotted as outliers (red crosses)
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