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Genetic voltage indicators

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Figure

Fig. 1 Historical overview of genetic voltage indicators. Sensors fall into three distinct families based on voltage sensing domains (VSD;microbial rhodopsins (refers to the activation wavelength reported in the paper or inferred from the spectrum of the f
Fig. 2 Recent VSD-based GEVIs.activity in a cortical neuron from an acute brain slice recorded with one-photon imaging
Fig. 3 Recent rhodopsin-based GEVIs.expression in pyramidal neurons in fixed postnatal brain slices.and 50 Hz (channelrhodopsin Cheriff (cells with overlay of both signals for the AP indicated by the arrow.voltage changes (Expression of Archon1 in acute br
Fig. 4 Chemogenetic voltage indicators. a Schematic representation of hVOS, consisting of a fluorescent protein anchored to the plasmamembrane, combined with a non-fluorescent synthetic compound dipicrylamine (DPA), which serves as a voltage-sensitive FRET

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