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Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma

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Academic year: 2020

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Figure

Fig. 1 Neutrophils predominantly infiltrated in the peritumoural tissue in patients with HCC
Fig. 2 A high level of neutrophil infiltration correlates with poor prognosis of patients with HCC
Fig. 3 PD-L1 expression was up-regulated on neutrophils in patients with HCC, and was negatively correlated with patients’ survival
Fig. 4 PD-L1 expression was up-regulated in hepatoma-bearing mice. a Neutrophils in mice were gated and analyzed according CD11b+Ly6G+.b Data shown was from tumour-bearing mice of PD-L1 expression on neutrophils in circulation and tissue
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