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Design, optimization, and validation of chemometrics-assisted spectrophotometric methods for simultaneous determination of etodolac and thiocolchicoside in pharmaceuticals

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Academic year: 2020

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Figure

Fig. 2 UV absorption spectra of the standard solutions added to the pharmaceutical preparation for ET (a) and TC (b)
Table 2 Analysis results of ET and TC in the validation set usingmultivariate calibration methods (PLS, PCR, and ILS)
Table 3 Correlation matrix and p values via Pearson for ET and TC
Fig. 4 UV absorption spectra of the drug (Etotio tablets) solutionscontaining ET (50 μg/mL and 75 μg/mL) and TC (1 μg/mLand 1.5 μg/mL)

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