• No results found

Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in <em>Caenorhabditis</em> <em>elegans</em> model of Huntington&rsquo;s disease

N/A
N/A
Protected

Academic year: 2020

Share "Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in <em>Caenorhabditis</em> <em>elegans</em> model of Huntington&rsquo;s disease"

Copied!
9
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Figure 1 structure of xyloketal B and compounds 1–6.
Figure 2 PolyQ-gFP protein distribution, survival rate and bending frequency in C. elegans huntington disease model, carrying different length of polyQ (Q16 and Q148).Notes: (A) aggregates can be seen all over the body wall muscle cells in Q148 worms
Figure 3 effect of xyloketal derivatives on stressed life span and motility in the C. elegans huntingotn’s diseasea model.Notes: (A) survival analysis of worms treated by compounds (or DMsO as negative control) using the Kaplan-Meier method
Figure 4 effect of xyloketal derivatives on htt aggregation.Notes: (A) Worms treated with 100 μM DMsO and other 100 μM compounds (1~6); both the number and the intensity of green foci decreased in drug-treated groups
+2

References

Related documents

Cub Scout Leaders have met the problem of no fund set for the Cub Scouting activities thereby resulting in the use of their personal fund for the good of scouting

A notable fact is that psychological and pedagogical support influenced on the change in attitude of all subjects of preventive education to people living with HIV. An analysis

BPC(BitPlane Coding) technique has been implemented in medical image compression. In this paper, presents a research overview of medical image compression using contourlet

pH showed good correlation with K + which indicates that the rampant annual bush burning is the common source of atmospheric pollution in the metropolis.. Therefore,

A deeper look at the underlying perceptions, attitudes and opinions nursery growers have about water broadly could provide insight into Extension education focusing on horticulture

Specialmente nel mito dei Titani, Dionisio appare come cifra della crisi sapienziale, che si esprime nella contraddizione maior , quella tra vita e morte.. Il bambino Dionisio

In recent years, the common tools for postoperative nursing guidance of knee replacement surgery include leaflets, manuals and video tapes of health education, computer

MapReduce is a simple yet powerful programming model designed for processing large scale datasets in a distributed.. and parallel