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Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71

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Figure

Fig. 1 Predicted RNA secondary structure of EV-A71 strain 41 from nt. 474 to 541. Due to slight differences in the length of the 5′-NTR, nt
Fig. 2 Cytopathic effects (CPE) caused by mutants a EV-A71 (A158T) b C475T c A486G d G487A e A5262G and f PD (Partial Deletant, 5′-NTR) inRhabdomyosarcoma (RD) cells in comparison with g uninfected RD cells (negative control using Opti-MEM) and h EV-A71 wi
Fig. 3 Quantification of Viral RNA Copy Number. Transfection of infectious RNA into RD cells was performed with the use of Lipofectamine 2000reagent and EV-A71 mutants at a MOI of 0.1
Table 1 Tissue Culture Infectious Dose50 (TCID50) of EV-A71mutants in comparison with the wild type EV-A71 strain 41
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