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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells

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Figure

Figure 1: Differential effects of mir-449a on cell cycle distribution in Pc-3 and DU-145 cells
Figure 2: DU-145 cells are resistant to mir-449a-induced cellular senescence. PC-3 and DU-145 cells were transfected with 50 nM concentrations of miR-Con or miR-449a for 72 hours
Figure 3: Wild-type rb sensitizes DU-1.1 and b5 cells to mir-449a-mediate cell cycle arrest
Figure 4: mir-449a triggers cellular senescence in DU-1.1 and b5 cells. DU-1.1 and B5 cells were transfected with mock, miR-Con, or miR-449a for 72 hours
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