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Distinct Notch signaling outputs pattern the developing arterial system

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Figure

Fig. 1. Notch signaling is active in early endothelial progenitors.(A-E) Confocal micrographs of flat-mounted expressing cells
Fig. 2. Notch activity increases and persists in arterial endothelial cellsat later developmental stages.(A,C,D); 50 showing Notch activation (green) and endothelial cells (red); DA, dorsalaorta; ISA, intersomitic artery; ISVe, intersomitic vein
Fig. 3. Cells exhibiting early Notch activation contributeto the dorsal aorta.30 hpf following exposure to tamoxifen at 10 ss for 1 hour.Left: blue fluorescence in all endothelial nuclei; middle: redfluorescence in lineage traced endothelial cells; right:
Fig. 5. deltacetv210 ng of  and dll4 have overlapping roles during arterydifferentiation
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