Curriculum Vitae. Last Updated: 03/24/2015. PERSONAL DATA Name: Aimee O. Hersh Citizenship: United States EDUCATION BOARD CERTIFICATIONS

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Curriculum Vitae

Last Updated: 03/24/2015 PERSONAL DATA

Name: Aimee O. Hersh Citizenship: United States EDUCATION

Years Degree Institution (Area of Study) 1993 - 1997 B.A. Whitman College (Spanish)

Walla Walla, WA

1997 - 2002 M.D. Brown Medical School (Medicine) Providence, RI

2000 - 2001 M.S. Dartmouth College (Clinical Epidemiology) Hanover, NH

2002 - 2005 Resident University of California, San Francisco (Pediatrics) San Francisco, CA

2005 - 2008 Fellow University of California, San Francisco (Rheumatology) San Francisco, CA

BOARD CERTIFICATIONS

01/01/2006 American Board of Pediatrics (Pediatrics), Certified

01/01/2008 American Board of Pediatrics (Sub: Peds Rheumatology), Certified ACADEMIC HISTORY

Pediatrics (Pediatric Immunology and Rheumatology)

10/05/2010 - Present Hire, Tenure Track - Clinician Scholar, Assistant Professor PROFESSIONAL EXPERIENCE

Full-Time Positions

2008 - 2010 Adjunct Instructor, Pediatric Rheumatology, University of California San Francisco, San Francisco, CA

2010 Assistant Professor, Pediatric Rheumatology, University of California, San Francisco, San Francisco, CA

2010 - Present Assistant Professor, Pediatric Rheumatology, University of Utah, Salt Lake City, UT 2015 - Present Division Chief, Pediatric Rheumatology, University of Utah, Salt Lake City, UT Reviewer Experience

Ad hoc referee for Arthritis Care and Research Ad hoc referee for Journal of Rheumatology Ad hoc referee for Pediatrics

SCHOLASTIC HONORS

1993 - 1997 Magna Cum Laude, Whitman College 1997 Phi Beta Kappa, Whitman College Chapter

2000 - 2001 Medical Student Research Fellowship, Sarnoff Endowment for the Cardiovascular Sciences 2002 Patricia McCormick Prize, Brown Medical School

2006 Alpha Omega Alpha, elected by UCSF School of Medicine 2006 Epstein Endowment for Clinical Research and Education

2007 American College of Rheumatology Distinguished Fellow Award

2008 - 2010 American College of Rheumatology Research and Education Foundation Physician Scientist Development Award

2010 - 2013 American College of Rheumatology Research and Education Foundation Rheumatology Investigator Award

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ADMINISTRATIVE EXPERIENCE Administrative Duties

2014 - Present Pediatric Guidance Council, Intermountain Healthcare, Member (Transition Subcommitee) Professional Organization & Scientific Activities

2006 - 2008 Executive Committee Member, American Academy of Pediatrics - Section on Rheumatology 2008 Grant Reviewer, American College of Rheumatology

2012 - Present Elected Member, Childhood Arthritis & Rheumatology Research Alliance, Protocol Evaluation Subcommittee

2015 - Present Vice-Chair, Childhood Arthritis & Rheumatology Research Alliance Grant Review Committee/Study Section

2013 - 2015 Reviewer for American College of Rheumatology Disease Targeted Research Study Section Symposium/Meeting Chair/Coordinator

2015 Childhood Arthritis Rheumatology Research Alliance (CARRA) Workgroup Leader PROFESSIONAL COMMUNITY ACTIVITIES

2014 - Present Co-Chair, Arthritis Foundation, Scientific Committee SERVICE AT PREVIOUS INSTITUTIONS

2008 - 2010 Interviewer, University of California, San Francisco, Intern Selection Committee 2008 - 2009 Member, University of California, San Francisco, Pediatrics Transition Task Force CURRENT MEMBERSHIPS IN PROFESSIONAL SOCIETIES

American Academy of Pediatrics American College of Rheumatology

Childhood Arthritis & Rheumatology Research Alliance FUNDING

Active Grants

01/01/13 - 01/31/17 Pediatric Vasculitis Initiative

Principal Investigator: Aimee O. Hersh Direct Costs: $2,013 Total Costs: $3,000 University of British Columbia

Role: Principal Investigator

01/01/14 - 02/19/17 Phase II Study of Rituximab for ANCA Vasculitis Principal Investigator: Aimee O. Hersh

Direct Costs: $146,705 Total Costs: $193,491 Hoffman-La Roche Inc

Role: Principal Investigator

06/01/14 - 05/31/19 Adult Outcomes of Juvenile Idiopathic Arthritis Principal Investigator: Aimee O. Hersh

Direct Costs: $128,240 Total Costs: $137,971

NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Role: Principal Investigator

Past Grants

07/01/06 - 06/30/07 Long-term outcomes of children with Systemic Lupus Erythematosus Principal Investigator: Aimee O. Hersh

National Institutes of Health Role: Principal Investigator

07/01/07 - 06/30/09 Loan Repayment Grant for Pediatric Research: Pediatric Lupus Outcomes Principal Investigator: Aimee O. Hersh

National Institutes of Health Role: Principal Investigator

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Principal Investigator: Aimee O. Hersh National Institutes of Health

Role: Principal Investigator

07/01/08 - 06/30/09 ACGME Challenge Grant. Transitioning Adolescent Patients from Pediatric to Adult Care: The UCSF-TAP Program.

Principal Investigator: Aimee O. Hersh Picker Institute

Role: Co-Principal Investigator

07/01/08 - 06/30/10 Development Award: Outcomes of Childhood-Onset Systemic Lupus Erythematosus Principal Investigator: Aimee O. Hersh

American College of Rheumatology Role: Principal Investigator

01/01/09 - 01/01/10 University Community Partnerships Council Community Engagement Grant: Preparing Patients with Chronic Illness and Disability for the Transition from Adolescence to Adulthood

Principal Investigator: Aimee O. Hersh University of California, San Francisco Role: Principal Investigator

07/01/09 - 06/30/10 Renewal, NIH Loan Repayment Grant for Pediatric Research Pediatric Lupus Outcomes Principal Investigator: Aimee O. Hersh

National Institutes of Health Role: Principal Investigator

07/01/10 - 06/30/13 Outcomes of Childhood-Onset Systemic Lupus Erythematosus: The Pediatric Lupus Outcomes Study (PLOS)

Principal Investigator: Aimee O. Hersh

Direct Costs: $319,519 Total Costs: $345,080 American College of Rheumatology

Role: Principal Investigator

07/01/11 - 06/30/12 Renewal, NIH Loan Repayment Grant for Pediatric Research Pediatric Lupus Outcomes Principal Investigator: Aimee O. Hersh

National Institutes of Health Role: Principal Investigator

06/01/13 - 05/31/15 The Learning Cohort: Assessing Patient Reported Outcomes in the CARRA Registry Direct Costs: $10,060 Total Costs: $14,989

Childrens Hospital Boston Role: Co-Investigator

01/15/14 - 05/31/14 Adult Outcomes of Juvenile Idiopathic Arthritis Principal Investigator: Aimee O. Hersh

Direct Costs: $75,000 Total Costs: $75,000

Rheumatology Research Foundation Bridge Funding Award Role: Principal Investigator

01/15/14 - 05/31/14 Adult Outcomes of Juvenile Idiopathic Arthritis Principal Investigator: Aimee O. Hersh

American College of Rheumatology Role: Principal Investigator

TEACHING RESPONSIBILITIES/ASSIGNMENTS Clinical Teaching

2011 - Present Clinical teaching and supervision of pediatric residents in both the in-patient setting and out-patient clinics.

Trainee Supervision Resident

2015 - Present Research Supervisor, Brad Nelson, University of Utah 2015 - Present Research Supervisor, Rebecca Overbury, University of Utah MD, PhD

2008 - 2009 PISCES Preceptor, Chris Jones, University of California, San Francisco 2008 - 2009 Clinical Supervisor, Megan Curran, University of California, San Francisco

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2008 - 2010 Clinical Supervisor, Mike Waterfield, University of California, San Francisco 2009 - Present Clinical Supervisor, Erica Lawson, University of California, San Francisco Medical Student

2012 - Present Research Supervisor, Spencer Cope, University of Texas Educational Lectures

Didactic Lectures

2011 - Present Presenter, Resident Noon Conference Continuing Education

CE Courses Developed

2014 - Present Audio Digest - Pediatrics Board Review. Collagen Vascular Disease and Other Multisystem Disorders.

PEER-REVIEWED JOURNAL ARTICLES

1. Panopalis P, Julian L, Yazdany J, Gillis JZ, Trupin L, Hersh A, Criswell LA, Katz P, Yelin E (2007). Impact of memory impairment on employment status in persons with systemic lupus erythematosus. Arthritis Rheum, 57(8), 1453-60.

2. Panopalis P, Yazdany J, Gillis JZ, Julian L, Trupin L, Hersh AO, Criswell LA, Katz P, Yelin E (2008). Health care costs and costs associated with changes in work productivity among persons with systemic lupus erythematosus.

Arthritis Rheum, 59(12), 1788-95.

3. Hersh AO, Pang S, Curran ML, Milojevic DS, von Scheven E (2009). The challenges of transferring chronic illness patients to adult care: reflections from pediatric and adult rheumatology at a US academic center. Pediatr Rheumatol

Online J, 7, 13.

4. Cabral DA, Uribe AG, Benseler S, O'Neil KM, Hashkes PH, Higgins G, Zeft AS, Lovell DJ, Kingsbury, DJ, Stevens A, McCurdy D, Chira P, Abramson L, Arkachaisri T, Campillo S, Eberhard A, Hersh AO, Huber AM, Kim S, Klein-Gitelman M, Levy DM, Li SC, Mason T, Hewitt EM, Muscal E, Nassi, L, Reiff A, Schikler K, Singer NG, Wahezi D, Woodward A (2009). For the ARChiVe investigator’s Network. Classification, Presentation and Initial Treatment of Wegener’s Granulomatosis in Childhood: An ARChiVe Project. Arthritis Rheum, 60(11), 3413-24.

5. Hersh AO, von Scheven E, Yazdany J, Panopalis P, Trupin L, Julian L, Katz P, Criswell LA, Yelin E (2009).

Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosus. Arthritis Rheum, 61(1), 13-20.

6. Cabral DA, Uribe AG, Benseler S, O'Neil KM, Hashkes PJ, Higgins G, Zeft AS, Lovell DJ, Kingsbury DJ, Stevens A, McCurdy D, Chira P, Abramson L, Arkachaisri T, Campillo S, Eberhard A, Hersh AO, Huber AM, Kim S, Klein-Gitelman M, Levy DM, Li SC, Mason T, Dewitt EM, Muscal E, Nassi L, Reiff A, Schikler K, Singer NG, Wahezi D, Woodward A (2009). Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood.

Arthritis Rheum, 60(11), 3413-24.

7. Yazdany J, Tonner C, Trupin L, Panopalis P, Gillis JZ, Hersh AO, Julian LJ, Katz PP, Criswell LA, Yelin EH (2010). Provision of preventive health care in systemic lupus erythematosus: data from a large observational cohort study.

Arthritis Res Ther, 12(3), R84.

8. Panopalis P, Gillis JZ, Yazdany J, Trupin L, Hersh A, Julian L, Criswell LA, Katz P, Yelin E (2010). Frequent use of the emergency department among persons with systemic lupus erythematosus. Arthritis Care Res (Hoboken), 62(3), 401-8.

9. Hersh AO, Trupin L, Yazdany J, Panopalis P, Julian L, Katz P, Criswell LA, Yelin E (2010). Childhood-onset disease as a predictor of mortality in an adult cohort of patients with systemic lupus erythematosus. Arthritis Care Res

(Hoboken), 62(8), 1152-9.

10. Lawson EF, Hersh AO, Applebaum MA, Yelin EH, Okumura MJ, von Scheven E (2011). Self-management skills in adolescents with chronic rheumatic disease: A cross-sectional survey. Pediatr Rheumatol Online J, 9(1), 35. 11. Mina R, von Scheven E, Ardoin SP, Eberhard BA, Punaro M, Ilowite N, Hsu J, Klein-Gitelman M, Moorthy LN,

Muscal E, Radhakrishna SM, Wagner-Weiner L, Adams M, Blier P, Buckley L, Chalom E, Chedeville G, Eichenfield A, Fish N, Henrickson M, Hersh AO, Hollister R, Jones O, Jung L, Levy D, Lopez-Benitez J, McCurdy D, Miettunen PM, Quintero-del Rio AI, Rothman D, Rullo O, Ruth N, Schanberg LE, Silverman E, Singer NG, Soep J, Syed R, Vogler LB, Yalcindag A, Yildirim-Toruner C, Wallace CA, Brunner HI (2012). Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus. Arthritis Care Res

(Hoboken), 64(3), 375-83.

12. Morishita K, Li SC, Muscal E, Spalding S, Guzman J, Uribe A, Abramson L, Baszis K, Benseler S, Bowyer S, Campillo S, Chira P, Hersh AO, Higgins G, Eberhard A, Ede K, Imundo L, Jung L, Kim S, Kingsbury DJ,

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Klein-Gitelman M, Lawson EF, Lovell DJ, Mason T, McCurdy D, Nanda K, Nassi L, O'Neil KM, Rabinovich E, Ramsey SE, Reiff A, Rosenkranz M, Schikler K, Stevens A, Wahezi D, Cabral DA (2012). Assessing the performance of the Birmingham Vasculitis Activity Score at diagnosis for children with antineutrophil cytoplasmic antibody-associated vasculitis in A Registry for Childhood Vasculitis (ARChiVe). J Rheumatol, 39(5), 1088-94.

13. Uribe AG, Huber AM, Kim S, O'Neil KM, Wahezi DM, Abramson L, Baszis K, Benseler SM, Bowyer SL, Campillo S, Chira P, Hersh AO, Higgins GC, Eberhard A, Ede K, Imundo LF, Jung L, Kingsbury DJ, Klein-Gitelman M, Lawson EF, Li SC, Lovell DJ, Mason T, McCurdy D, Muscal E, Nassi L, Rabinovich E, Reiff A, Rosenkranz M, Schikler KN, Singer NG, Spalding S, Stevens AM, Cabral DA (2012). Increased sensitivity of the European medicines agency algorithm for classification of childhood granulomatosis with polyangiitis. J Rheumatol, 39(8), 1687-97.

14. Morishita K, Guzman J, Chira P, Muscal E, Zeft A, Klein-Gitelman M, Uribe AG, Abramson L, Benseler SM, Eberhard A, Ede K, Hashkes PJ, Hersh AO, Higgins G, Imundo LF, Jung L, Kim S, Kingsbury DJ, Lawson EF, Lee T, Li SC, Lovell DJ, Mason T, McCurdy D, O'Neil KM, Punaro M, Ramsey SE, Reiff A, Rosenkranz M, Schikler KN,

Scuccimarri R, Singer NG, Stevens AM, van Mater H, Wahezi DM, White AJ, Cabral DA (2012). Do adult disease severity subclassifications predict use of cyclophosphamide in children with ANCA-associated vasculitis? An analysis of ARChiVe study treatment decisions. J Rheumatol, 39(10), 2012-20.

15. Bennett TD, Fluchel M, Hersh AO, Hayward KN, Hersh AL, Brogan TV, Srivastava R, Stone BL, Korgenski EK, Mundorff MB, Casper TC, Bratton SL (2012). Macrophage activation syndrome in children with systemic lupus erythematosus and children with juvenile idiopathic arthritis. Arthritis Rheum, 64(12), 4135-42.

16. Okumura MJ, Hersh AO, Hilton JF, Lotstein DS (2013). Change in health status and access to care in young adults with special health care needs: results from the 2007 national survey of adult transition and health. J Adolesc Health,

52(4), 413-8.

17. Son MB, Johnson VM, Hersh AO, Lo MS, Costenbader KH (2014). Outcomes in hospitalized pediatric patients with systemic lupus erythematosus. Pediatrics, 133(1), e106-13.

18. Lawson EF, Hersh AO, Trupin L, von Scheven E, Okumura MJ, Yazdany J, Yelin EH (2014). Educational and vocational outcomes of adults with childhood- and adult-onset systemic lupus erythematosus: nine years of followup.

Arthritis Care Res (Hoboken), 66(5), 717-24.

19. Lange L, Thiele GM, McCracken C, Wang G, Ponder LA, Angeles-Han ST, Rouster-Stevens KA, Hersh AO, Vogler LB, Bohnsack JF, Abramowicz S, Mikuls TR, Prahalad S (2016). Symptoms of periodontitis and antibody responses to Porphyromonas gingivalis in juvenile idiopathic arthritis. Pediatr Rheumatol Online J, 14(1), 8.

20. Smits-Seemann RR, Kaul S, Hersh AO, Fluchel MN, Boucher KM, Kirchhoff AC, Smits-Seemann RR, Kaul S, Hersh AO, Fluchel MN, Boucher KM, Kirchhoff AC (2016). ReCAP: Gaps in Insurance Coverage for Pediatric Patients With Acute Lymphoblastic Leukemia. J Oncol Pract, 12(2), 175-6.

REVIEW ARTICLES

1. Hersh A, von Scheven E, Yelin E (2011). Adult outcomes of childhood-onset rheumatic diseases. [Review]. Nat Rev

Rheumatol, 7(5), 290-5.

2. Hersh A (2011). Measures of health-related quality of life in pediatric systemic lupus erythematosus: Childhood Health Assessment Questionnaire (C-HAQ), Child Health Questionnaire (CHQ), Pediatric Quality of Life Inventory Generic Core Module (PedsQL-GC), Pediatric Quality of Life Inventory Rheumatology Module (PedsQL-RM), and Simple Measure of Impact of Lupus Erythematosus in Youngsters (SMILEY). [Review]. Arthritis Care Res (Hoboken), 63

Suppl 11, S446-53.

BOOK CHAPTERS

1. Hersh AO, Lawson EF (2012). PFAPA. In Curbside Consultation in Pediatric Infectious Disease: 49 Questions. 2. Lawson EF, Hersh AO (2012). Recurrent Fevers. In Curbside Consultation in Pediatric Infectious Disease: 49

Questions.

OTHER (Commentary/Letters/Editorials/Case Reports/Video/Film) Editorials

1. Hersh A, Yazdany J (2009). Putting Guidelines into Practice in the Treatment of Rheumatoid Arthritis. Journal of Rheumatology. J Rheumatol, 36(5), 863-4.

2. Hersh AO (5/1/2014). Growing Up and Moving On-- Transition of Care for Patients with Childhood-Onset Rheumatic Disease. Journal of Rheumatology.

PENDING PUBLICATIONS Journal Articles

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Systemic Lupus Erythematosus: Case Definition and Guidelines for Data Collection, Analysis, and Presentation of Immunization Safety Data. Vaccine.

Review Articles

1. Hersh AO (In Press). Patient reported outcomes in Juvenile Idiopathic Arthritis. [Review]. Rheum Dis Clin North Am. Abstracts

1. Valentine KJ Murray M, Hersh AO, Reynolds C, Clark EB (In Press). Prevalence and Cost of Serious Chronic and

Mental Health Conditions in Adolescents Seen Within an Intergrated Healthcare System [Abstract]. Pediatrics.

Commentary

1. Hersh AO (In Press). Systemic Juvenile Idiopathic Arthritis. Year Book of Pediatrics. RECENTLY PUBLISHED ABSTRACTS (Last 3 Years)

1. Lawson EF, Trupin L, Hersh AO, Scheven Ev, Yelin EH, Yazdany J (2014). A168: systemic lupus erythematosus

in-hospital mortality risk across ages: a national estimate [Abstract]. Arthritis Rheumatol, 66 Suppl 11, S217.

2. Hersh AO, Son MB, von Scheven E (2014). A85: effect of childhood-onset systemic lupus erythematosus on linear

height and body mass index [Abstract]. Arthritis Rheumatol, 66 Suppl 11, S118.

3. Angeles-Han ST, McCracken C, Pichavant M, Jenkins K, Ponder L, Myoung E, Stevens KR, Vogler LB, Kennedy C, Yeh S, Cope S, Bohnsack JF, Hersh AO, Thompson SD, Prahalad S (2014). A123: HLA Associations in a Matched

Cohort of Juvenile Idiopathic Arthritis Children With and Without Uveitis [Abstract]. Arthritis Rheumatol, 66 Suppl 11, S160-1.

ORAL PRESENTATIONS

Invited/Visiting Professor Presentations Local/Regional

2014 Utah Rheumatology Alliance

Grand Rounds Presentations

2012 Pediatric Grand Rounds, Primary Children's Hospital OTHER SCHOLARLY ACTIVITIES

Clinical Studies

2011 - Present Site PI, ARCHIVE and Brainworks Vasculitis Registry Studies 2013 - Present Site PI, Phase II Study of Rituximab for ANCA Vasculitis Other Scholarly Activities

2014 - Present Brighton Collaboration, International Vaccine Safety Collaborative

2014 - Present US Bone and Joint Decade, The Burden of Musculoskeletal Diseases in the United States, Contributor

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