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Potts Disease Case Study OLGC

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Anatomy and Physiology

The spinal cord is the largest nerve in the body, and it is comprised of the nerves which act as the communication system for the body. The nerve fibers within the spinal cord carry messages to and from the brain to other parts of the body. The spinal cord is surrounded by protective bone segments, called the vertebral column. The vertebral column is comprised of seven cervical vertebrae, twelve thoracic vertebrae, five lumbar vertebrae and five sacral

vertebrae. The vertebral column also provides attachment points for muscles of the back and ribs. The vertebral disks serve as shock absorbers during activities such as walking, running and jumping, they also allow the spine to flex and extend.

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Introduction

Potts disease

 Is a spine infection associated with tuberculosis that is characterized by bone destruction, fracture, and collapse of the vertebrae, resulting in kyphotic deformity.

 Is the presentation of the extra-pulmonary tuberculosis arthritis of the intervertebral joints

Also called tuberculosis spondylitis, tuberculous spondyloarthropathy, spinal TB, musculoskeletal tuberculosis

The causative agent is Mycobacterium Tubercule

 Particularly the lower thoracic and the upper lumbar regions are affected.  Commonly localized in the thoracic 11 and thoracic 12.

The original name was formed after Percivall Potts a London surgeon.  Patient with BCG has 80% immunity.

Pathognomonic Sign: Gibbus Formation

 Signs and Symptoms: Back Pain, Fever, Night Sweating, Anorexia, Weight Loss, Spinal mass, sometimes associated with numbness, tingling, or muscle weakness of the legs  Diagnostic Exam: Blood Test: elevated erythrocyte sedimentation rate, Tuberculin test,

Bone Scan, Radiographs of the spine, CT of the spine, Bone biopsy, MRI

 Predisposing Factors: Direct contaminant especially in children, Malnutrition, Poor Environmental Condition, Trauma

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Nursing History

1. Personal Data

Name: Ms. RB Age: 3y/o Sex: Female

Address: Sto. Tomas Santiago, Batangas Occupation: N/A

Religion: Roman Catholic

Date and Time of admission: March 5, 2009 4:30pm Admitting Physician: Dr. HM

2. Chief Complaint

Fever and Back pain

3. History of Present illness

5 months before hospitalization the patient felled from the stairs. The patient’s mother brought her to a “manghihilot”.

2 weeks before hospitalization the patient’s mother have seen a mass at the patient’s back, the patient had fever and accompanied with back pain. The mother decided to go to the doctor for consultation.

1 day before hospitalization the patient’s mother went to the hospital and was referred to Phil. Orthopedic Center. The patient was admitted at children’s ward and scheduled for CBC and x-ray of the thoracolumbar spine.

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4. Past Medical History

The patient’s mother always consults “Manghihilot” when her daughter is sick. The mother has lack of interest in going to health center to seek medical consultation when her daughter is sick.

5. Family Medical History

The mother and father of the patient self-medicates when there are sick, the mother said that there family has never been hospitalized. The father works as a construction worker, smoke cigarettes at least 3-4 sticks a day. The mother stays at home to take care of her 5 children.

Pathophysiology

Pulmonary Tuberculosis Spread of Mycobacterium Tubercule in the T7-T9 of the spine Extra-pulmonary Tuberculosis The infection spreads from intervertebral disc

Pus formation between the intervertebral disc Back Pain, Fever, Night

Sweats, Spinal mass

Disc tissue dies and broken down by

caseation Vertebral NarrowingVertebral CollapseSpinal DamagePotts’ Disease

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Laboratory / Diagnostic Examinations

March 5, 2009

Blood Chemistry Normal Value Result Findings

Component: -Hemoglobin mass -Leucocyte count Differential count: -Segmenters -Lymphocyctes -Monocytes -Eosinophils -Platelet count 110-150 g/L(female) 4.5-10 x 10 g/L 0.50-0.70 0.20-0.40 0.00-0.07 0.00-0.05 150-400 x 109/L 125 g /L 16.90 g/L 0.45 0.42 0.08 0.05 532 x 109/L Normal

May indicate infection

Normal

May indicate infection May indicate infection Normal

May indicate inflammatory disease

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April 16, 2009

Blood Chemistry Normal Value Result Findings

Component: -Hemoglobin mass -Hematocrit -Leucocyte count Differential count: -Segmenters -Lymphocyctes -Monocytes -Eosinophils -Platelet count 110-150 g/L(female) 0.37-0.54 4.5-10 x 10 g/L 0.50-0.70 0.20-0.40 0.00-0.07 0.00-0.05 150-400 x 109/L 129 g/L 0.40 13.6 x 10 g/L 0.45 0.50 0.01 0.04 375 x 109/L Normal Normal

May indicate infection

Normal

May indicate infection Normal

Normal Normal

March 5, 2009

Urinalysis Normal Value Result Findings

Electrolytes: Sodium Potassium Chloride 135-148 mmol/L 3.5-5.3 mmol/L 98-107 mmol/L 139.7 mmol/L 3.98 mmol/L 101.7 mmol/L Normal Normal Normal March 10, 2009

Urinalysis Normal Value Result Findings

Color

Transparency Specific Gravity Reaction

Straw to Dark yellow Slightly Hazy 1.002-1.006 Light yellow Hazy 1.003 Acidic Normal Normal Normal

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March 12, 2009 X-ray of the Thoracolumbar spine

Impression: Pneumonitis, both lower lung zone with lyphadenopathies Consolidation vs. Extension of paravertebral abscess, right lower lung zone Potts disease, as described, T6-T11

March 24, 2009 CT scan of the Thoracic spine

Impression: Findings as consistent with Potts disease T8-T9 with pulmonary extension as described

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Drug Study

Classification Dosage Mechanism of Action

Indication Contraindication Adverse Reaction Nursing Consideration Generic Name: Rifampicin Brand Name: Anti-infectives 200mg/5ml syrup 6ml OD ac PO Rifampicin inhibits DNA-dependent polymerase, decreases replication Maintenance phase treatment of all forms of pulmonary and extra-pulmonary tuberculosis(TB) Hypersensitivity, jaundice, severe hepatic disease GI disturbances, pseudomembranous colitis (rare), abnormalities of liver function, fatalities in those with liver disorders, influenza-like symptoms, skin reactions, eosinophilia, transient leucopenia, thrombocytopenia, purpura, shock, drowsiness, headache, ataxia, visual disturbances, menstrual irregularities. Reddish colored urine and tears. IV: Thrombophloebitis; extravasation following local irritation and inflammation. >Assess lung sounds and character and amount of sputum periodically during therapy >Assess results of periodic laboratory tests and chest x-ray, therapeutic effectiveness and adverse reactions >Monitor patient compliance with treatment regimen

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Classification Dosage Mechanism of

Action Indication Contraindication Adverse Reaction ConsiderationNursing Generic Name: Isoniazid Brand Name: Anti-infectives 200mg/5ml syrup 6ml OD ac PO Isoniazid inhibits RNA synthesis, decreases tubercule bacilli replication Pulmonary and extra-pulmonary tuberculosis(TB)

Acute liver disease or history of hepatic damage during INH therapy; hypersensitivity Peripheral neuritis, optic neuritis; psychotic reactions, convulsions, nausea, vomiting, fatigue, epigastric distress, visual disturbances, fever, rash, pyridoxine deficiency >Assess laboratory examinations >Monitor liver/renal function >Assess CNS often >Assess hepatic status

>Assess for visual disturbance that may indicate optic neuritis

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Classification Dosage Mechanism of

Action Indication Contraindication Adverse Reaction ConsiderationNursing Generic Name: Paracetamol Brand Name: Analgesics 125mg/5ml syrup 5ml Q4 PRN PO Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS. Treatment of fever Hypersensitivity Stimulation, drowsiness, nausea, vomiting, abdominal pain, hepatotoxicity, hepatic seizure, renal failure, luekopenia, neutropenia, hemolytic anemia, thrombocytopenia, pancytopenia, rash, urticaria, hypersensitivity, cyanosis, anemia, neutropenia, jaundice, pancytopenia, CNS stimulation, delirium followed by vascular collapse, convulsions, coma, death >Assess patient’s fever >Assess for allergic reactions >Assess hepatotoxicity >Monitor liver and renal functions

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Nursing Care Plan

Assessment Diagnosis Inference Planning Intervention Rationale Evaluation

Subjective:

“Kulang daw siya sa timbang sabi ng doctor” as verbalized by the mother Objective: -Under weight -Lack of interest in eating nutritious food Imbalanced Nutrition less than body

requirements related to ingest adequate nutrients Pulmonary Tuberculosis Weakens immune system Generalized weakness Loss of appetite Imbalanced Nutrition After 8hrs of Nursing Interventions the patient will demonstrate a behaviors to achieve appropriate weight

-Assess weight, age, body build, strength, activity/rest level -Discuss eating habits, including food preferences to the mother -Administer Vitamins as ordered -Encourage and provide for frequent rest periods

-Encourage small, frequent meals with food high in protein and carbohydrates -Provide oral care before/after meals at bedtime

-To provide

comparative baseline -To appeal to the patients likes

-To enhance patients intake

-To conserve energy, especially in metabolic requirements -To maximize nutrient intake without undue fatigue

-To reduce bad taste left from the

medications used in respiratory treatment After 8hrs of Nursing Interventions the patient has demonstrated a behaviors to achieve appropriate weight

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Assessment Diagnosis Inference Planning Intervention Rationale Evaluation Subjective: “Nilagyan siya ng Taylor Brace” as verbalized by the mother Objective: -Limited range of motion -Difficulty in turning -Presence of Taylor Brace Impaired Physical Mobility related to therapeutic restrictions of movement Pulmonary Tuberculosis Spread of Mycobacterium Tubercule in the spine Extra-pulmonary Tuberculosis Infection spreads from the intervertebral disc Pus formation between the intervertebral disc Disc tissue dies and

broken down by caseation Vertebral Collapse Spinal Damage Impaired Physical Mobility After 4hrs of Nursing Interventions the patient’s mother will verbalize

understanding of the situation and

treatment regimen and safety measures

-Encourage to change position every 2 hours -Schedule activities with adequate res periods

-Provide regular skin care -Provide passive exercises -Encourage adequate intake nutritious foods

-Explain the use of adjunctive devices such as Taylor Brace

-To prevent complications -To reduce fatigue

-To promote good hygiene

-To maintain muscle integrity

-To maximize energy production -To promote knowledge and enhances safety After 4hrs of Nursing Interventions the patient’s mother has verbalized

understanding the situation and treatment regimen and safety measures

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References

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