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Development and Validation of a Stability-indicating RP-HPLC Method Using Quality by Design for Estimating Captopril

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Figure

Fig. 1: Ishikawa diagram showing factors that may impact key method attributes
TABLE 2: CODED LEVELS FOR THE CCD EXPERIMENTAL DOMAIN AND RESULTANT RESPONSES
TABLE 3: ANOVA DATA FOR RESPONSE SURFACE QUADRATIC MODEL FOR RETENTION TIME
Fig. 3: Normal plot (A) of residuals for retention time of CP and (B) plot of predicted vs
+3

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