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Quantitative analysis of lab to lab variability in Caco 2 permeability assays

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Figure

Table 1. Analytical methods including HPLC-UV and liquid-liquid extraction procedures for studied compounds
Table 2. Dose and formulation input parameters of application set compounds for GastroPlus TM simulation
Table 3. P app values of training set compounds from our laboratory and six different literature datasets
Table 4. Caco-2 P app values and simulated F a values of application set compounds Compounds Caco-2Papp(× 10-6cm/s)a
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