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Discussion Document: July 6, 2009

Nano Startup Challenge in Cancer (NSC

2

) Overview

By: Rosemarie Truman,

Founder and CEO, The Center for Advancing Innovation

OCTOBER 2

nd

, 2015

the center for

advancing i nnovation

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2 Proprietary and Confidential to The Center for Advancing Innovation. Do not distribute

Goals of The NSC

2

• Nanotechnology and Cancer Focus: Accelerate the translation and development of nanotechnology

solutions for the early detection, diagnosis, and treatment of cancer

• Collaborative Environment: Advance the translation of cancer nanotechnologies by developing

collaborations* between industry, research, academia, etc. and creating a forum for knowledge

exchange

• Economic Growth: Spur economic growth through new startups and jobs

• Entrepreneurship Learning: Provide entrepreneurial education programs for scientists

• Business Model: Leverage new business model to advance Federally-funded inventions through

startup challenge

• Technology Transfer Memorandum: “Accelerate and increase the volume of Federally funded

technology transfer in support of high growth businesses”

*involving not only the Federal Government but also companies, health systems, patient advocacy organizations, philanthropists, state governments, research universities, private research institutes, and scientific societies

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3 Proprietary and Confidential to The Center for Advancing Innovation. Do not distribute *Inventions can be found in the USPTO and criteria are listed on http://www.NSCsquared.org

Overview of Phases: 500+ people enter;

we expect approximately 15 startups

Phase 0: Enter Challenge

Phase 1: Elevator Speech

Phase 2:

Business Plan Phase 3: Startup Post-Contest Oct. 12th 2015 – Feb 11th 2016 Feb. 12th – Apr. 4th 2016 Apr. 5th – Jul. 18th 2016 Jul. 19th – Aug. 28th 2016 Post Aug. 28th 2016 Teams: • Select an NIH furnished invention or find an invention* • Form a team involving

medical, business and entrepreneur disciplines • Enter challenge 30 Teams per Invention Invention 1

5 Teams per Invention Move Forward

• CAI provides training and mentoring • Teams produce:

• Elevator speech • Executive

summary

• Entries undergo public voting

• CAI evaluates

3 Teams per Invention Move Forward-

• CAI conducts continued training • Advisors perform Q&A • Teams produce a

Business Plan and associated pitch • Judges evaluate

proposals/teams and select winners

• CAI provides prize

Invention 1

Up to 3 Startups for Each Invention

Winners and finalists: • Revise Business Plans • Launch startup

• Raise seed funding leveraging investors CAI has established

• Apply for a license • Enter accelerators “Startup Winner” Has Licensing Agreement and Seed Funding New startups: • Potential to collaborate with inventors** • Develop and commercialize a product • Impact the standard of care

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Partners of the Nano Challenge and Past Challenges

NCI partnered with CAI to launch the Neuro and Breast Cancer Startup Challenges, and provided inventions that were the bases of both challenges. The Nano Startup Challenge in Cancer will involve inventions from NCI, NIBIB, and academia.

Mission to accelerate and increase the volume of invention commercialization. Holds nine Partnership Intermediary Agreements across HHS to identify promising inventions and assist in commercialization. Partnered with NIH to orchestrate the Breast Cancer and Neuro Startup Challenges in the past.

Judges and Advisors (Past Challenges)

Challenge Partners

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We have several testimonials from the participants of past challenges

Participating in the Neuro-Startup Challenge these past few months has broadened the horizons of each team member of NeuroCognetix, and inspired new goals and desires for commercializing new technologies through

successful startup businesses. The Challenge provided an interesting learning experience and a compelling

opportunity to interact with accomplished business leaders, NeuroCognetix

The Neuro Startup Challenge originally offered us an avenue to learn about Biotechnology and Small Businesses through a hands-on experience. We were able to apply our different backgrounds to start a business. However, by the end, the challenge offered us something so much more. With their mentoring and relationships, the Neuro Startup Challenge gives EncepHeal Therapeutics the opportunity to help over 22 million people affected by substance abuse, many of which, do not have options when it comes to FDA treatments, EncepHeal

The Breast Cancer Startup Challenge (BCSC) has truly been the greatest experience of my academic and

professional career. I have been successful in many academic competitions in the past, however the BCSC has

set up teams for success unlike any other competitionGoing forward, we should all look forward to the foundation of many great startups from similar CAI and NIH Startup Challenges. OncoLinx

I feel that the Breast Cancer Startup Challenge (BCSC) is one of the most well-organized start-up challenges

conducted. Right from initial selection of participating teams until announcement of winners and subsequent start-up mentorship, at each step, Rosemarie and her team represent clarity of vision, structured planning and near perfect implementation, Heragen

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How you can participate?

1. Tell your friends and colleagues from your alma mater, labs, etc.

2. Spread the news while attending conferences

3. Update your LinkedIn network to encourage participation

4. Suggest a Mentor, Advisor, or Judge for the Challenge here:

https://form.jotform.com/52824326349964

5. Participate:

Form a team and enter

Be a mentor, judge and/or advisor

Elevator Speech Phase: Provide constructive criticism to teams

Business Plan Phase: Listen in on one of the live pitches

Proprietary and Confidential to The Center for Advancing Innovation. Do not distribute

Find Team Members Here

Nanotechnology Startup Challenge in Cancer

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