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Accelerated Bioprocess Development

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Table 1. Cultivation details. The experimental conditions regarding each mini-bioreactor are shown, including the fed-batch profile, feed rate, initial substrate concentration S0 and occurrence of a hunger phase
Figure 1. Schematic overview of the feed profiles. In the first feed phase exponential (green), linear (orange) or constant feed (blue) is applied according to the experimental plan, followed by a constant feed (here after 5 h) for all cultivations in the
Figure 2. The robotic HT platform for cultivation in 48 MBRs and automated sampling and analysis
Figure 3. Measurement data is shown regarding the designs 1, 2 and 3 – exponential feed with feed rates of (a) 0.0875 h-1, (b) 0.175 h-1 and (c) 0.35 h-1, initial substrate concentration S0 = 30 g L-1 and no hunger phase
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