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Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPD

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Academic year: 2020

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Figure

Figure 1 Cs-exposed mice develop the hallmarks of COPD and skeletal muscle atrophy.Notes: (A) lung sections of the Cs-group and control mice stained with h&e
Figure 3 reduced mrna levels of Igf1, Acta1, and Myh2 mrna in Cs-exposed mice.Notes: The mrna levels of Igf1, Acta1, and Myh2 were quantified in the quadriceps muscle of control and CS-group mice by real-time reverse transcription polymerase chain reaction
Figure 4 The expression of sTars and rhoa protein in Cs-exposed and control mice.Notes: Western blot analysis showed that the protein levels of sTars and rhoa in the quadriceps muscle of Cs-group mice were markedly lower than those in the control group

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