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Use of transdermal and intravenous granisetron and the ability of the Hesketh score to assess nausea and vomiting induced by multiday chemotherapy

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Figure

Table 1 Demographics and baseline characteristics of patients in a phase III trial receiving their first cycle of a new multiday moderately or highly emetogenic regimen (n = 393)
Figure 1 Emetogenicity (percentage of patients expected to experience emesis) of multiday, multiagent chemotherapy regimens by overall Hesketh scores1 of 2, 3, 4, or 5 on each day of chemotherapy (scores determined by the emetogenic potential of each chemotherapeutic agent administered each day).
Figure 2 Emetogenicity (percentage of patients expected to experience emesis) of the four most emetogenic multiday, multiagent chemotherapy regimens by individual Hesketh scores1 of 1, 2, 3, 4, or 5 on day 1 of chemotherapy (logistic regression analysis)
Figure 3 Classification tree for Hesketh scores,1 showing that the best binary predictor of emetogenicity over the period at risk was the most emetogenic agent given on day 1.

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