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Dual delivery of active antibactericidal agents and bone morphogenetic protein at sustainable high concentrations using biodegradable sheath-core-structured drug-eluting nanofibers

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Academic year: 2020

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Figure 1 Fabrication process of sheath-core-structured nanofibers.Notes: (A) schematic of the experimental setup
Figure 2 SEM micrographs of the drug-eluting PLGA nanofibers.Notes: Morphologies and diameter distributions of (A) sheath-core-structured nanofibers and (B) blended nanofibers.Abbreviations: seM, scanning electron microscopy; Plga, poly(d,l)-lactide-co-glycolic acid.
Figure 3 TEM image of sheath-core-structured nanofibers (× 60,000).Abbreviation: TeM, transmission electron microscope.
Figure 5 The water contact angles on electrospun nanofibrous membranes.Notes: Water contact angles of (A) virgin PLGA nanofibers (114.7°), (B) sheath-core-structured drug-eluting nanofibers (81.6°), and (C) blended drug-eluting nanofibers (82.3°).Abbreviation: Plga, poly(d,l)-lactide-co-glycolide.
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