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Dynamics of 5 carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification

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Figure

Figure 1. Dynamics of enzymatic 5mC oxidation during hepatic differentiation. (A) Co-detection of 5caC with 5hmC and DAPI (upper row) or of the indicated differentia-0.001;tion markers with DAPI (middle row and lower row for HEP ENDO 96 h stage) in undiffe
Figure 2. 5caC accumulates at promoter regions of hepatocyte markers at the onset of their expression
Figure 3. Nuclear distribution of 5hmC and 5caC during speciplot showing 5caC:5hmC colocalization coef(HEP ENDO 24 h)
Figure 4. 5caC staining intensity does not correlate with the levels of HNF-4a expression during hepatic endoderm commitment
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