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Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis

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Academic year: 2020

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Figure

Figure 1. 1. Pre-replication complex (preRC)
Figure 2. where licensing is actively inhibited by high CDK activity. The permissive activity range for CDKFigure2. Quantitative model of CDK activity define cell cycle transitions. Cyclin‐CDK activityoscillates  through  the  cell  cycle  defining  key  t
Table 1. Ciz1 is associated with tumor growth in multiple cancers. A summary of evidence ispresented showing the effect of Ciz1 overexpression or depletion of Ciz1
Figure 3. Ciz1 may contribute to DNA replication stress via stimulation of oncogenic transcription and(deregulation of the cell cycle
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