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0.5mg/ml 0.5mg/ml gege tata inin A) A) 150mg/hr150mg/hr B) B) 300mg/hr300mg/hr C) C) 2.5mg/hr2.5mg/hr D) D) 5mg/hr5mg/hr ti ti ouou thth 100mg/QID 100mg/QID 5050mgmg/$/$ 0.0.3030 40mg/BID 40mg/BID 20mg/$20mg/$ 00450045 12 12mgmg/$/$ 0.0.9191 B o B o C &C & -W -W e a e a Eq.wt Eq.wt it it inin g#g# oMRoMR q5q5 lala irir nsns -T -T gSgS gS gS Pr

(2)

Rx Rx On

Ondadansnsetetroro HCHC ch

chererryry sysyruru 6 t 6 t ) 9) 9 2 t2 t 0 t0 t ma ma 5 d 5 d 5 d5 d s s s s )3 )3 re

renana clcleaeararancnce,e, ifif atat enen 2 L 2 L 6 L6 L 9 L9 L e o e o 1 L 1 L ) 2) 2 c) c) .4.4 d)d)1.1.2323 daday- y-b)0 b)0.5.5 mimin-n- -1-1 d)d)3.3. mimin- n-MgC0 MgC0 Pr

(3)

0 m 0 m (Mg (Mg 84.384.3 A-4.3g A-4.3g has has ri ri hu

humama ininteteststininalal flflorora?a? b ) b ) e)

e) PsPseueudodomomonana aeaerurugiginonosasa

)C )C he

hemomolylytiti didiseseasas

b) b) ) L ) L es es rmrm ) V ) V re re c) c) d)6d)6 fo fo rere il

ilatatatatioio atat thth ininititiaia haha acacutut ininflflamammama ioio I-I- I- I-I o I o ) I) I I oI o I aI a I oI o , I, I , a, a Pr Pr tetectct coco riri htht anan rere enen iriracac

(4)

E-E-T4T4 cecellll )G )G c) c) ChCh lele erer d)

d) CaCarbrbohohydydraratete

Pr

(5)

part part an

anotothehe tytypepe

il il b)

b) DeDe rereasas popotatassssiuiu pepermrmeaeabibililityty c)

c) InIn rere sese popotatassssiuiu pepermrmeaeabibililityty

ti

ti tete

B.

B. prpropopylylththioioraracici

E.

E. prprololonongege exexpoposusu toto olol enenviviroronmnm ntnt

st st

ro

(6)

b)

b) c)c) e)e)

synthetase synthetase

a)

a) 1,21,25-d5-dyhyyhyroxroxychycholeolecalcalcifciferoero b)

b) 25-25-hydhydroxroxychycholeolecalcalcifciferoero c)

c) 7-d7-dehehydydrorochchololesesteteroro d)

d) ChChololesescacalclcififererolol

reaction reaction ac

(7)

tissue? tissue?

c)

c) NoNorerepipinenephphririnene

a)

a) DeDetotoxixifificacatitionon b)

b) GlGlucucononeoeogegenenesisi ig ig th th di diclcl fefenana B.

B. PrPropopoxoxypyphehenene C.

C. IbuprofenIbuprofen D.

D. InIndodomemeththacacinin E. E. NaproxenNaproxen te te ltlt isis ny ny xexedede oror hy

hypopogogonanadidismsm ip ip ti ti le le tutu le le lala itit 53

53-Wh-Whicic ofof thth olollolo inin bebestst dedescscriribebe thth coco didititionon knknowow hyhypopoprprotothrhromom ininememinin ta

(8)

to

to chchararacacteteririzeze thth heheadadacachehe A.

A. TuTumomoririgegenini B.

B. VaVascsculularar-m-migigrarainin C.

C. MuMuscsc onontrtracac ioio

A.

A. hyhypepertrthyhyroroididisis C.

C. hyhypopoththyryroioididismsm ad

adrerenana ypypererplplasasiaia

-Wh -Wh

I o

I o ) I) I I oI o

wo

woulul inincrcreaea thth ririsksk hehemomorrrr agage?e? A. A. -Wh -Wh hyperkalemia? hyperkalemia? II

III.I. sosodidiumum popolylyststyryrenen susulflfononatat I o

I o ) I) I d Id II oI o I oI o , a, a

-Th -Th

Pr

(9)

-W -W infection? infection?

A.

A. efefototetetanan (c(cefefototanan B.

B. efeftrtr axax nene (R(R cecephphinin C.

C. ErErytythrhromomycycinin

-W -W su

suffffererinin frfromom didiababeteteses memellllititusus

C.

C. urur arar etetenentitionon ly

lycoco urur

62

62-P-Patat enentsts ususinin mimi dadaririnene (C(C rdrdararonone)e) shshououldld momoninitotorere fofo

) I

) I ) I) I I oI o I aI a I oI o I aI a I oI o e)e) not

not ncnc ududeded thth ecechnhnicic anan rere popo sisibibililititieses am

ambubulalatotoryry cacarere prpracactiticece B.

B. ReRe omommeme didingng ththererapapeueu icic alal erernanatitiveve hehe rerescsc ibibinin phphysysicic anan In

In enen oror mamainin enenanancece 64

64-A-A haharmrmacac stst eeee toto dede titifyfy anan erer-t-t e-e-coco ntnterer ugugarar-f-freree,e, alalcoco olol-f-frere cocougug foformrm lala co

co tata niningng guguaiaifefenene inin anan dede trtromometethohorprpanan owow cocoulul hihi ueueststioio bebe clclasas ifif eded A.

A. AvAvaiailalabibililityty B.

B. StStororagageses/s/statabibililityty D.

D. CaCalclcululatatioio

A.

A. PhPhararmamaceceututicicalal alalteternrnatativiveses B.

B. PhPhararmamacece titicaca eqequiuivavalele tsts C.

C. ThThererapapeueutiti alalteternrnatativiveses D.

D. ThThererapapeueutiti eqequiuivavalelentnt Bi

Bi lologigicaca eqequiuivava enen

Pr

(10)

a. a. FillersFillers c. c. LubricantsLubricants d. d. DispersantDispersant gr

grananululatatioio isis

-W -W -W -W -Wh -Wh 2-W

2-W icic hehe fofo lolowiwingng roroututeses ofof adadmimininiststrara ioio prpr vividede fofo hehe rereatateses ioioavavaiailalabibililityty

st

(11)

74

74-A-A lalargrg vovolulu IVIV vo volulu eses oror orore?e? a. a. 1010mlml it it tete tete toto trtr -W -W lo lo isis sususpsp of

of itit seseveverere totoxixi itity?y?

-Wh -Wh titi ll ll sysy thth lolo it it Copyright Copyright

(12)

B. B.

E. E.

di

dissssololututioio raratete

Fl

Fl ccccululatateded sususpspenen ioionsns

f t f t

(13)

f t f t

f t f t

a.

a. elelaxaxatatioio brbronon hihialal smsmoooo mumu clcl anan roroncnc odod lalatiti

-Wh -Wh

A-A-SuSu tata rere eaea sasagege frfr

B-B-CoContntrorolllleded rereleleasaseded dodosasagege foformrm So

Solulu onon agag foformrm

D-D-SlSlowow rere eaeasese sasa foformrm E-M

E-Micicroroememululsisionon dodosasagege foformrm ch

ch thth fofo owow rere onon eses isis memedidiatateded rara mpmpatat eteticic mumu cacariri rerececeptpt rsrs

ac ac atatioio e)

(14)

HC

HC anan epep inin gege

e)

e) MuMucucu anan epep ininogogenen

include include I.I. II. II. III. III. days days , I , I E-fatigue E-fatigue be

be yoyourur rerecocommmmenendadatitionon

b)

b) acacetetamamininopophehe

- 2 - 2

(15)

To

Totaltal liliabiabililitietie $75,000$75,000

ur

urrere liliabab lili ieie

02

02 nsns rara coco papaninieses ayay oror thth ruru heapheapeses riricece tititutu eded meme icicatat s.s.

of$0.60/tablet of$0.60/tablet $1.90/tablet $1.90/tablet . 3 . 3O/tabletO/tablet of$0.50/tablet of$0.50/tablet 3.

3. olol inin arar imimpoportrtanan unun amamenentata ririncncipip eses mama keketiti PTPT

ri

ri ryry cocontnt enencece isis NONO agaggrgravavatateded byby

I o

I o ) I) I I oI o I oI o

lu

lu ioio onon aiai ntntamam cicin,n, etet ylyl ararabab n,n, soso iuiu enenzozoatate,e, anan didi didi ed

edenentatatete CoCorrrr ctct atatemem ntnt(s(s bobo atat lulu ioio mama clcludud

I o

I o ) I) I I oI o I oI o , a, a

- 2 - 2

(16)

I o

I o ) I) I I aI a I oI o I oI o , a, a

dr

dr iningege tete ororalallyly

Ca

Carbrb dodopapa isis avavaiai abab e,e, fofo ararenen ereralal adadmimi isistrtratatioio

A.

A. CaCarbrb dodopapa crcr sssseses thth lolo rarainin babarrrr erer

Ca

Carbrbididopop avavaiailala lele fofo ararenen ereralal adadmiminini trtratatioio

E. E. -W -W glaucoma. glaucoma. 11

112-2- 3-3- eaear-r-olol mamalele rerecece vivingng ylylenen ap

apprpr prpriaia chch icic fofo coco ststipipatat onon asassosociciatateded itit cocodede nene

Pr

(17)

-W -W re

reduducece teteroroidid osos

ma ma I o I o I oI o )1)1 114-114- E.E. ColiColi 11

116-W6-W icic hehe fofollllowowinin tata ememenen abab utut rara hyhypopoglgl cecemimicscs arare/e/isis cocorrrrecec

A-A-ChChlolorprproropapamimidede blblococksks ininsusulili rerececeptptoror

B-B-GlGlipipizizidid inincrcreaeasese glglucucagagonon sesecrcretetioionsns -T

-T

1l

1l7-7-MeMe abab lili prpr duductct ofof iaiacici ncnc udude:e: I o

I o I oI o III-NicotineIII-NicotineI oI o )1)1 18

18-I-I igig xixin,n, inincrcreaeasese inin hyhydrdroxoxylyl grgr upup haha ncncrereasaseses ololararitity!y! -I

-Incncrereasas duduraratitionon acactitionon B-D

B-Dececrereasas duduraratitionon ofof acactitionon C-N

C-N

mi mi

1-1-L-HisL-Histadtadineine decdecarbarboxyoxylaslas

II-L-II-L-hishistadtadineine carcarboxboxylaylasese III-L-h

III-L-hististidiidinene hydhydroxroxylaylasese I o

I o ) I) I I oI o I aI a I oI o I oI o )1)1 -T

-T

A-A-SeSelelectctiviv COCO nhnhibibitit

B-B-SeSe ecectitiveve COCO IIII nhnhibibitit

D-D-AceAcetyty latlat cyccycloolooxygxygenaenasese

E-E-InInhihibibitsts lilipopoxyxygegenanasese asaswewellll asas cycyclclooooxyxygegenanasese 12l-Serotonin:

12l-Serotonin: A-Imidazole

A-Imidazole B-tryptophanB-tryptophan

Pr

(18)

E-pyrrolidine E-pyrrolidine

) I

) I IIII I aI a I oI o IIII IIII

12

123-3-FiFilglgraraststinin isis

mu mu momo Erythropoietins Erythropoietins D-OprelvekinE-mo mo

I-I- ememogoglolobibi (o(oxyxygege cacarrrr erer blblooood)d)-p-poror hyhyriri tete rarameme II

II-M-Myoyoglglobobinin (o(oxyxygege cacarrrrieie inin titissssueue)-)-momononomemer.r.

II

II -C-Cytytocochrhromom oxoxididasase.e.

) I

) I IIII I aI a I oI o IIII , I, I IIII

A-A-PoPosisititiveve scschihizozophphrerenini sysympmptotomsms

B-B-NeNegagatitiveve scschihizozophphrerenini sysympmptotomsms

C-C-PoPosisititiveve anan nene atat veve sysympmptotomsms D-De

D-Deprpresessisionon anan scschihizozophphrerenini

E-E-SeSeizizurureses anan dedeprpresessisionon

jec jec Comprehensiveness Comprehensiveness -T -T -T -T Copyright Copyright - 2- 2

(19)

profit profit

l-l-BaBalalancnc shsheeee

II-II-ReRetatainin eaearnrninin ststatatememenen II

III-I-InIncocomeme ststatatememenen I o

I o I oI o 1,1,

33

33-W-W atatisis SFSF-3-3 36

36 E-E-PaPatitienen nono clclininicicalal ininfoformrmatatioio

C-C-GeGenenerara hehealalthth ststatatusus D-D-ShShoror fufuncnctitionon

mp

mp rtrtanan memetata ololisis reacreac ioion.n. ThTh trtranansfsferer tete raracycyclcl nene epep -t-tetetraracycyclcl nene caca lele

13

135-5-SiSimemeththiciconon isis pr

prototecectitiveve agagenen

D-D-BlBloooo didilalatitionon cacaususeses ananeueuryrysmsm 139.

139. ErytErythromyhromycin:cin:

I-I- isis rorotete sysyntnthehe isis nhnhibibititoror

19 19

(20)

II

II isis efeffefectctiviv agagaiainsns grgramam-p-p sisititiveve cococccci.i. ) I

) I I aI a I oI o onlyonly e)e)1,1, IIII anan

14

141-1- icic OTOT ncnc ududeded ststatat ststicic

-A -Anana ysysisis ofof -Yo -Yo -N -Namam upup lilierer mg/ml? mg/ml? Copyright Copyright - 2- 2 2020

(21)

fo

foodod cocontntaiaininingng hihighgh cacarbrbohohydydraratetes.s.

-Le -Le

E-R

E-Refeferer erer ememerer enencycy

co

confnfididenentitialalitity)y) -Y

-Y

Se

(22)
(23)
(24)

References

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