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Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

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Figure

Table 1 Clinical characteristics of child bearing group (female 19 to 39 years) from NDNS and pregnant women fromSaudi population
Figure 2 Effect of vitamin B12 on cholesterol biosynthesis. (A) Total cholesterol from adipocytes cultured in customised media: control (500 nMB12), LB (0.15 nM B12), and NoB (0 nM B12)
Figure 3 Effect of vitamin Bas triplicates. Values are mean ± SEM. *12 on regulation of cholesterol biosynthesis
Figure 4 Effect of vitamin B12 on methylation of cholesterol regulatory genes. Genome-wide DNA methylation analysis of cholesterolregulatory genes was performed in adipocytes cultured in customised media, control, LB, and NoB
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