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Trackable and Targeted Phage as Positron Emission Tomography (PET) Agent for Cancer Imaging

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Figure

FIGURE 1. (A) Rationale for developing PET trackable phage nanoparticles. (B) The synthetic scheme of DOTA-/AmBaSar-T7-RGD
FIGURE 2. (A) Binding between T7-RGD phage and integrin αvβ3. (B) Confocal microscopic images of fixed SKOV3 ovarian cancer cells labeled with 488 conjugated wild type T7 (left, the exposure of control sample was further extended to study the weak binding
FIGURE 3. (A) Coronal microPET images of nude mouse bearing U87MG tumor at 1 h, 4 h, and 16 h p.i
FIGURE 4. Coronal microPET images of nude mouse bearing U87MG tumor at 1 h, 4 h, 16 h, and 24 h p.i

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