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Interaction of MSC with tumor cells

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Figure

Fig. 1 Indirect interactions between mesenchymal stroma/stem cells and cancer cells. a Cytokines, chemokines, growth factors: MSC secrete aplethora of soluble factors that can bind as substrates to appropriate receptors on the cell surface of cancer cells
Fig. 2 Direct interactions between mesenchymal stroma/stem cells and cancer cells. a Notch signaling: A prominent example for direct cell-to-
Fig. 3 Formation and culture of tumor hybrid cells after spontaneous cell fusion. a Co-culture of MSCGFP with MDA-MB-231cherry breast cancercells demonstrating the development of fusion cells which are indicated by white arrows

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