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Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy

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Figure

Table 1 Modulation of drug resistance to Dox by Verapamil and Cyclosporine A in HMECd1 and HMECd2
Figure 1 Induced P-gp-mediated drug resistance of endothelial cells.lines, the P-gp surface expression and the Rho efflux were regularly analyzed by flow cytometry, as shown in Figure 2a-d (RHMECd1, and HMECd2
Figure 2 Endothelial cells express functional P-gp protein. Panel a and b: Verapamil blocks Rho efflux in endothelial cells
Figure 3 Induction of P-gp expression and its involvement in tumor growth in mice.experiment was performed without the 15-day pretreatment in mice receiving only NaCl (group V) or Dox (group VI)

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