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miR-133a Regulates Vitamin K 2,3-Epoxide Reductase Complex Subunit 1 (VKORC1), a Key Protein in the Vitamin K Cycle

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Figure

Figure 1. Reporter plasmids and miRNA binding sites in 3representation of the reporters used for the study
Table 1. Specific scores, free energy values and characteristics of the VKORC1 3′UTR/miRNAs binding.
Figure 2. Validation and specificity of VKORC1 mRNA-miRNA interaction in HepG2 cells.(A) HepG2 cells were transfected with precursor molecules for miR-133a and with an SCRat three different concentrations
Figure 4. Reporter studies of the direct VKORC1 mRNA-miRNA interaction. (A) pMIR-as mean ± SD from four (A) and six (B) experiments performed in triplicate

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