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The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses

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Figure

figure 1: Adenovirus structure and transcription regions. A) Adenovirus capsid is composed of three major and four minor proteins
Table 1: Triggered innate inflammatory pathways.
Figure 3: Interferon induction during adenovirus infection. In plasmacytoid DC adenoviral DNA activates TLR9 in plasmacytoid DCs, whereas DAI is activated in mDCs

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