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Enhanced IFN α production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus

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Academic year: 2020

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Figure

Table 1 Characteristics of healthy controls (HC) and patientswith systemic lupus erythematosus (SLE)
Fig. 1 Toll-like receptor (TLR)9-induced interferon-α (IFN-α) production
Fig. 2 Toll-like receptor 7 (TLR7)-induced interferon-active disease (pDCs were compared between patients with glomerulonephritis(GN) or other manifestations, in all patients (****comparisons test).imiquimod-induced INF-Disease Activity Index 2000 (SLEDAI)
Fig. 5 Interferon-cells (pDCs). Imiquimod or CpG-induced IFN-Values in graphs indicate percentages of IFN-α (IFN-α) enhanced imiquimod-induced IFN-α production and suppressed CpG-induced IFN-α production of plasmacytoid dendriticα-producing capacity of pDC
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