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The long and the short of aberrant ciliogenesis in Huntington disease

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Figure

Figure 1Structure of primary and motile secondary cilia. Primary and motile secondary cilia differ in the structure of their axoneme
Figure 2Mutant Htt and loss of normal Htt have opposing effects on ciliogenesis. Keryer and colleagues showed that mutant Htt drives increased ciliogen-esis and the formation of hypermorphic primary cilia, whereas loss of Htt results in reduced ciliogenesi

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