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Valosin containing protein and neurofibromin interact to regulate dendritic spine density

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Figure

Figure 1The density of dendritic spines is reduced in Nf1+/– heterozygous mice. (A) First branches, (B) second branches, and (C) the remaining higher-order branches of apical dendrites of CA1 pyramidal cells
Figure 2VCP interacts with neurofibromin. (
Figure 3Reduction of VCP expression impairs dendritic spine formation. (A) Knockdown effect of the VCP miRNA construct in HEK293T cells
Figure 4Overexpression of the neurofibromin-binding domain of VCP inhibits spine formation
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