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PPARγ regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1

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Figure

Figure 1OLR1 is induced by PPARγ ligands in 3T3-L1 adipocytes. (A) Comparison of OLR1 and aP2 mRNA levels in 3T3-L1 preadipocytes (Pread), adipo-cytes treated with vehicle (DMSO), and rosiglitazone-treated adipocytes (Rosi)
Figure 2The OLR1 promoter-enhancer is TZD-responsive. (A) Schematic of reporter constructs containing serial truncations of the OLR1 promoter-enhancer fused to luciferase (Luc)
Figure 3The proximal PPARwild-type and mutant oligonucleotide probes corresponding to the puta-tive PPARin contain PPARnucleotides contain point mutations in the putative PPARfor specific mutations, see Methods
Figure 4Rosiglitazone regulates the recruitment of corepressors and coactivators to the endogenous
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