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BRAIN DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW ON RECENT EXPERIMENTAL AND CLINICAL FINDINGS

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Figure

FIG. 1:  THE MAJOR PATHS FOR THE TRANSPORT OF MOLECULES ACROSS THE BBB ARE SHOWN. (1) TRANSPORT PROTEINS: THE ENDOTHELIAL CELLS CONTAIN CARRIER PROTEINS FOR CHOLINE, AMINO ACIDS, GLUCOSE, PURINE BASES, NUCLEOSIDES, ETC
FIG. 2:  OVERVIEW OF DIFFERENT APPROACHES OF BRAIN TARGETING; (ANS- AUTONOMIC NERVOUS SYSTEM; CNS- CENTRAL NERVOUS SYSTEM; BBB- BLOOD BRAIN BARRIER; MABS- MONOCLONAL ANTIBODIES)
TABLE 1: BRIEF ACCOUNT ON DRUG MOLECULES BEING USED BY SEVERAL APPROACHES FOR BRAIN TARGETING
FIG. 3: BBB CMT SYSTEMS ARE SHOWN FOR SEVEN DIFFERENT CLASSES OF NUTRIENTS AND THE GENES FOR FIVE OF THESE SYSTEMS HAVE BEEN IDENTIFIED
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