1918-19 Influenza Pandemic
A geographic analysis of population density thresholds in the influenza pandemic of 1918–19
... the influenza pandemic of 1918 – 19 in India The 1918–19 influenza pandemic was one of the worst epidemics in history with an estimated global mortality between 20 ...
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The evolution of pandemic influenza: evidence from India, 1918–19
... of 1918, and the clear pattern by which they demonstrate that the disease originated in Bombay and spread out across India from there (see Figure 2 and the Additional file 1: Video clip in the “Results” section ...
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Prior immunity helps to explain wave like behaviour of pandemic influenza in 1918 9
... of influenza can provide partial protection against a new pandemic strain ...different influenza strains has also been invoked to help explain the apparent constraints on the evolutionary ...
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Prior immunity helps to explain wave-like behaviour of pandemic influenza in 1918-9
... of influenza can provide partial protection against a new pandemic strain ...different influenza strains has also been invoked to help explain the apparent constraints on the evolutionary ...
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Experimental Infection of Pigs with the Human 1918 Pandemic Influenza Virus
... the 1918/rec virus, which is known to induce lethal infection upon experimental inoculation in ferrets and macaques (14, 38), was not highly virulent in pigs, indicating a potential resistance of swine to highly ...
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Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses
... with pandemic viruses, gene expression continued to increase following infection, resulting in a 2-fold difference in expression levels from those of the seasonal viruses at later time ...the 1918 strain ...
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Differential Activation of NK Cells by Influenza A Pseudotype H5N1 and 1918 and 2009 Pandemic H1N1 Viruses
... 2009 pandemic H1N1 than that of H5N1 and 1918 ...of influenza viruses (12, 19, ...to influenza virus infection, and a dosage-dependent manner was found for NK cell activation by ...of ...
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The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways
... the 1918:Tx/ 91(NS) virus relative to mock-infected ...the 1918 virus compared with that observed in mock-infected cells, indicating that the 1918 NS1 protein sup- pressed even low-level, ...
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Spatial temporal excess mortality patterns of the 1918–1919 influenza pandemic in Spain
... measurable pandemic mortality impact in respiratory or all-cause data during May-July 1918 in both the Canary and Balearic Islands (Table ...the pandemic virus was not intro- duced into these Spanish ...
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Time variations in the transmissibility of pandemic influenza in Prussia, Germany, from 1918–19
... Equation (2) is a slightly different expression of a method proposed for SARS [15]. The advantages of this model include: (i) we only need to know the time of onset of cases (i.e. the model does not require the total ...
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Intranasal Vaccination with 1918 Influenza Virus-Like Particles Protects Mice and Ferrets from Lethal 1918 and H5N1 Influenza Virus Challenge
... and 1918 viruses by the HI assay with ...or 1918 virus was incubated with twofold serial dilutions of sera, starting at a 1:10 dilution, and incubated overnight on MDCK cells ...
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The age distribution of mortality due to influenza: pandemic and peri-pandemic
... H1N1 pandemic [10] and individuals older than 26 years were reported to be spared in the mini-pandemic re-emergence of H1N1 viruses in 1977/8 ...an influenza virus emerged with pan- demic effect, a ...
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Structural Characterization of the 1918 Influenza Virus H1N1 Neuraminidase
... The overall structures of NAs are very well conserved among different subtypes of influenza A viruses, as are those from influenza B viruses, despite sequence identities as low as 30% (7). A previous study ...
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MCEIRS PANDEMIC H1N INFLUENZA TRAINING
... The USDA APHIS Veterinary Services National Poultry Improvement Plan (NPIP) coordinates efforts by state officials and commercial industry on programs to monitor and test domestic poultry to detect the occurrence of ...
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Virulence determinants of pandemic influenza viruses
... of influenza A viruses to adapt to various hosts and undergo reassortment events ensures constant generation of new strains with unpredictable degrees of pathogenicity, transmissibility, and pandemic ...of ...
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The influenza epidemic of 1918 and the adivasis of Western India
... In 1918, the epidemiology of influenza was poorly ...that influenza was caused by a bacillus, identified as Pfeiffer’s ...in 1918 was focussed in the wrong direction. 27 The influenza ...
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the Pandemic COVID-19 Disease
... and Ongoing Mutations in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-. 742[r] ...
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Proteolytic Activation of the 1918 Influenza Virus Hemagglutinin
... the 1918 HA NA pseudotypes was strictly dependent on trypsin activation ...the 1918 influenza virus, recruits plasminogen present in FCS and facilitates generation of plas- min, which in turn ...
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Elicitation of Anti-1918 Influenza Virus Immunity Early in Life Prevents Morbidity and Lower Levels of Lung Infection by 2009 Pandemic H1N1 Influenza Virus in Aged Mice
... human influenza viruses require adaptation to cause dis- ease in mice, except for highly pathogenic viruses, including 1918 and H5N1 isolates ...2009 pandemic virus also readily in- fects mice, ...
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Rapid detection of pandemic influenza in the presence of seasonal influenza
... The pandemic model was simulated 10 times for the whole of Great Britain, starting on day 1 seeded with a single infection at a randomly chosen ...the pandemic start week as the week when the first ...
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