3′-untranslated region
The isolation and function of the 3'untranslated region of the myosin heavy chain genes of skeletal muscle
... 5’ untranslated region. Now that the 3’ untranslated region has become a focus for an additional mechanism of controlling gene expression, the RNA protein interactions of these regions ...
265
Comparison of single nucleotide polymorphisms in the 3′ untranslated region of HLA G in placentas between spontaneous preterm birth and preeclampsia
... the 3 ′ untranslated region (3 ′ UTR) of HLA-G have been observed ...the 3 ′ UTR of the HLA-G between pregnancies complicated with sponta- neous preterm births and those with ...
5
The 3' untranslated region of picornavirus RNA: features required for efficient genome replication.
... the 3 * untranslated region (3 * UTR) in the replication of enteroviruses has been studied with a series of mutants derived from either poliovirus type 3 (PV3) or a PV3 replicon ...
10
An RNA tertiary structure in the 3' untranslated region of enteroviruses is necessary for efficient replication.
... (C 3 A or C 3 G) gave rise to RNA which, despite several transfections, yielded no infectious ...CC 3 GU), was also produced and shown to be noninfectious, again following several ...GG 3 CA), ...
8
Similar Interactions of the Poliovirus and Rhinovirus 3D Polymerases with the 3′ Untranslated Region of Rhinovirus 14
... the 3⬘ UTRs are diverse with re- gard to length and structure ...the 3⬘ structures formed fall into three main groups, the primary and secondary structures within each group being very highly con- served ...
7
Mitochondrial Aconitase Binds to the 3′ Untranslated Region of the Mouse Hepatitis Virus Genome
... Partial colocalization of nucleocapsid protein and m-acon- itase early in infection. Dual-labeling experiments were carried out to visualize the localization of MHV replication in relation to m-aconitase. The MHV ...
11
Mutations in the E2 Glycoprotein and the 3′ Untranslated Region Enhance Chikungunya Virus Virulence in Mice
... sites, 3 for clusters and tracts of leukocytes coalescing into at least one large area that displaces/replaces tissue, with or without necrosis and with or without mineralization, and 4 for leukocytes that are in ...
17
Structural Domains within the 3′ Untranslated Region of Turnip Crinkle Virus
... loop region of helix H5 lead to its distortions away from the helical form, and, past the ...the 3 ⬘ end of the modeled ...the 3 ⬘ end is even more pronounced (not ...loop region and the ...
15
Characterization of an Essential RNA Secondary Structure in the 3′ Untranslated Region of the Murine Coronavirus Genome
... the 3⬘ UTR of the BCoV genome that is essential for DI RNA ...same region of RNA and that one is a switch regulating the other, perhaps governing transition between different steps of viral replica- ...the ...
11
Regulation of thrombospondin-1 expression through AU-rich elements in the 3′UTR of the mRNA
... the 3’-untranslated region (3’UTR) of the TSP-1 mRNA suggests that post-transcriptional regulation is likely to represent one mechanism by which TSP-1 gene expression is ...TSP-1 3’UTR ...
14
Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk
... the 3¢-untranslated region (3¢-UTRs) predicted NO excretion, as well as autonomic traits: baroreceptor coupling, maximum pulse interval, and pulse interval variability, though not ...
15
miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer’s disease
... the 3′ untranslated region (UTR) of their target mRNA transcripts by partial se- quence complementarity (resulting in destabilization of the mRNA and/or inhibition of translation) ...seed ...
11
Original Article Genetic polymorphism analysis of CYP2J2 drug-metabolizing enzyme in a Chinese Zhuang population
... and 3’-untranslated region of the CYP2J2 gene in 100 unrelated healthy Zhuang individuals and identified 16 different CYP2J2 polymorphisms in the Zhuang population, in which including one novel ...
7
Detection of a new mutation in the beta myosin heavy chain gene in an individual with hypertrophic cardiomyopathy
... distal 3'-end of the beta MHC gene yielded an additional product in the DNA template from the proband which was subsequently cloned and ...the 3'-untranslated region and the polyadenylation ...
11
Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses
... 5′ untranslated region; 3′-UTR: 3′ untranslated region; ORF: the open reading frame; eIF4G: eukaryotic translation initiation factor 4 gamma; NF-κB: nuclear factor kappa B; NEMO: ...
13
Molecular Comparison of Three Different Regions of the Genome of Infectious Bronchitis Virus Field Isolates and Vaccine Strains
... gene 3 and nucleocapsid (N) gene along with 3' untranslated region (3' UTR) were amplified and subjected to restriction fragment length polymorphism (RFLP) using three different ...gene ...
9
Original Article Tagging functional SNPs rs191876689 in MTHFR decrease risk of ischemic stroke
... Abstract: Objective: Functional polymorphisms located in MTHFR have been identified to be highly associated with the risk of ischemic stroke (IS). In this study, we mainly focused on the miRNA associated MTHFR ...
5
A miR-SNP of the <em>XPO5</em> gene is associated with advanced non-small-cell lung cancer
... the 3′ untranslated region (3′ UTR) of the miRNA processing machinery gene XPO5 was examined in 112 advanced non-small-cell lung cancer (NSCLC) patients to evaluate its association with cancer ...
5
The U Rich Untranslated Region of the Hepatitis E Virus Induces Differential Type I and Type III Interferon Responses in a Host Cell Dependent Manner
... the 3= untranslated region (UTR) of the HEV genome induced higher levels of IFN mRNA, interferon regulatory factor-3 (IRF3) phosphorylation, and nuclear translocation than the 5= UTR of ...
15
Multiple functions of a glioblastoma fusion oncogene
... the 3′–untranslated region (3′- UTR) of FGFR3 is lost, releasing FGFR3 signaling from miR-99a–depen- dent inhibition and greatly enhancing tumor progression relative to WT ...
5