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Crossover safety study of aprepitant: 2-min injection vs 30-min infusion in cancer patients receiving emetogenic chemotherapy

<p>Crossover safety study of aprepitant: 2-min injection vs 30-min infusion in cancer patients receiving emetogenic chemotherapy</p>

... the 30-min HTX-019 infusion group (IVI), 8 TEAEs were reported after the start of chemotherapy administration in 5 of 135 patients (4%) (patients IVI1-5), the most com- mon being erythema (n=2) and dyspnea ...

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Poliovirus morphogenesis. I. Identification of 80S dissociable particles and evidence for the artifactual production of procapsids.

Poliovirus morphogenesis. I. Identification of 80S dissociable particles and evidence for the artifactual production of procapsids.

... S v a I u RSB pH 7.4 for 30 min at 40C RSB pH 7.4 for 30 min at 40C + 0.02 M EDTA RSB pH 7.4 for 30 min at 40C + 0.1% SDS RSB pH 7.4 for 30 min at 370C RSB pH 8.5 for 30 min at 40C Empty[r] ...

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Design, Synthesis, and Anti-RNA Virus Activity of 6 '-Fluorinated-Aristeromycin Analogues

Design, Synthesis, and Anti-RNA Virus Activity of 6 '-Fluorinated-Aristeromycin Analogues

... After being stirred at room temperature for 30 min, the reaction mixture was quenched with saturated aqueous NH 4 Cl (30 mL) and diluted with EtOAc (30 mL).. The layers.[r] ...

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Specific secretion of polypeptides from cells infected with vaccinia virus.

Specific secretion of polypeptides from cells infected with vaccinia virus.

... Order of the samples: A, uninfected cell profile after a 30-min pulse; B, uninfected cell profile after a 30-min pulse in the presence of CAR following treatment for 5 h with 25 pg of CA[r] ...

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Synthesis, Characterization, and Activity of Tin Oxide Nanoparticles: Influence of Solvothermal Time on Photocatalytic Degradation of Rhodamine B

Synthesis, Characterization, and Activity of Tin Oxide Nanoparticles: Influence of Solvothermal Time on Photocatalytic Degradation of Rhodamine B

... particles was evaluated through the degradation of 5 mg/L Rhodamine B (RhB) in a BL-GHX-V multifunc- tional photochemical reactor (Shanghai Bilon Experi- ment Equipment Co. Ltd., Shanghai, China). The volume of the ...

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Localization of two cellular forms of the vesicular stomatitis viral glycoprotein.

Localization of two cellular forms of the vesicular stomatitis viral glycoprotein.

... a [35S]methionine-labeled cytoplasmic VSV proteins from intermediate density membranes p = 1.175 of infected cells labeled for 30 min and chased for 30 min 10 -48-h exposure; b [35S]meth[r] ...

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Impregnation and mechanical properties of three softwoods treated with a new fire retardant chemical

Impregnation and mechanical properties of three softwoods treated with a new fire retardant chemical

... at 30 min for Sugi, 60 min for Korean pine, and 30 min for Hinoki, respectively, regardless of position and impregnation pressure ...

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Nonstructural proteins of Semliki Forest virus: synthesis, processing, and stability in infected cells.

Nonstructural proteins of Semliki Forest virus: synthesis, processing, and stability in infected cells.

... The markers for A: a ts-1induced proteins labeled for 1 min in isotonic medium after 30 min treatment with 335 mM NaCl and chased for 60 min; b ts-1-induced proteins labeled with the win[r] ...

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Interleukin-8 Induces the Endothelial Cell Migration through the Activation of Phosphoinositide 3-Kinase-Rac1/RhoA Pathway

Interleukin-8 Induces the Endothelial Cell Migration through the Activation of Phosphoinositide 3-Kinase-Rac1/RhoA Pathway

... (1 min to 10 ...5 min group and 10 min group. Both in 15 min group and 30 min group, lamellipodium could be found at the leading edge of migrating ...

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Hypoxia tolerance and preconditioning are not additive in the trout
(Oncorhynchus mykiss) heart

Hypoxia tolerance and preconditioning are not additive in the trout (Oncorhynchus mykiss) heart

... following 30·min of severe hypoxia include: (1) 5·min of hypoxia was an insufficient period of time to elicit a preconditioning response in these trout hearts; and/or (2) these in situ hearts were ...

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Gone but not forgotten: the lingering effects of intermediate term memory on the persistence of long term memory

Gone but not forgotten: the lingering effects of intermediate term memory on the persistence of long term memory

... That is, snails, a 15 min training procedure with a 30 min interval if an extinction procedure was given to the snails after the between three training sessions results in memory that pe[r] ...

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Cross Talk between PML and p53 during Poliovirus Infection: Implications for Antiviral Defense

Cross Talk between PML and p53 during Poliovirus Infection: Implications for Antiviral Defense

... Poliovirus infection induced the recruitment of Sp100 and p53 to PML NBs and a decrease in p53 expression only. The poliovirus-induced increase in PML NB size suggests the re- cruitment of cellular proteins in these ...

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Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice

Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice

... not 30-min incubation, suggests that Rab3D participates in the first phase of pancre- atic acinar exocytosis, such as priming zymogen granules for docking, or fusion to plasma ...at 30 min is ...

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Acute pharmacotherapy of migraine, tension-type headache, and cluster headache

Acute pharmacotherapy of migraine, tension-type headache, and cluster headache

... The attacks of cluster headache are short-lived (maxi- mum 3 h) and non-oral routes of administration of drugs should be used. Subcutaneous sumatriptan is the most effective treatment, but very costly, see above. In one ...

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Autoantibody facilitated cleavage of C1 inhibitor in autoimmune angioedema

Autoantibody facilitated cleavage of C1 inhibitor in autoimmune angioedema

... Patient CI-Inh incubated for 30 min at 370C in PBS is illustrated in track 1; normal inhibitor also incubated for 30 min at 370C in track 5; protease incubated under the same conditions,[r] ...

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Eugenol hyperactivated nymphs of Triatoma infestans become intoxicated faster than non hyperactivated nymphs when exposed to a permethrin treated surface

Eugenol hyperactivated nymphs of Triatoma infestans become intoxicated faster than non hyperactivated nymphs when exposed to a permethrin treated surface

... 66.75 min for acetone pre-treated controls, and 46.27 min for eugenol pre-treated nymphs); ...(a.ii.) 30 min after topical application of eugenol (KT50: 66.79 min for controls, and ...

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Apelin 12 improves metabolic and functional recovery of rat heart after global ischemia

Apelin 12 improves metabolic and functional recovery of rat heart after global ischemia

... This work was designed to explore efficacy of apelin-12 (A-12) as a cardioprotective agent when given before ischemia or at reperfusion using the isolated working heart model. Hearts of male Wistar rats were subjected to ...

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Introducing physically active lessons in UK secondary schools : feasibility study and pilot cluster-randomised controlled trial

Introducing physically active lessons in UK secondary schools : feasibility study and pilot cluster-randomised controlled trial

... Open access Week 0 Baseline measures Week 1 Week 4 Training session 2 2 hours 30 min: Sharing PAL experiences 30 min: Outdoor PAL examples 20 min: Indoor PAL examples 20 min: Discussion [r] ...

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Spectrum of Physical Properties Among the Virions of a Whole Population of Vaccinia Virus Particles

Spectrum of Physical Properties Among the Virions of a Whole Population of Vaccinia Virus Particles

... Sedimentation of the virus in 15 to 30% sucrose at 12,600 rev/min for 30 min advanced the peak of single particles to the 450-ml zone, providing the additional data necessary for computa[r] ...

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Survival of Staphylococcus aureus on the outer shell of fire fighter turnout gear after sanitation in a commercial washer/extractor

Survival of Staphylococcus aureus on the outer shell of fire fighter turnout gear after sanitation in a commercial washer/extractor

... 10 min soak/sanitizing cycle at 105 °F was programed into the washer/extractor followed by a 4-min spin cycle extraction at low speed (G-force < ...

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