5′ untranslated region
The 5′ Untranslated Region of the Major Immediate Early mRNA Is Necessary for Efficient Human Cytomegalovirus Replication
... mRNA 5= untranslated region (5= UTR) plays an important role in regulating mRNA ...shared 5= UTR of the IE1 and IE2 mRNAs (MIE 5= UTR) in regulating ...MIE 5= UTR ...
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Important Factors in Reliable Determination of Hepatitis C Virus Genotype by Use of the 5′ Untranslated Region
... The 5= untranslated region (UTR) of HCV RNA is used in commercial genotyping, but the probes and the lengths of the amplicons are proprietary and vary among the ...the 5= UTR were ...the ...
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Nucleotide Variability and Translation Efficiency of the 5′ Untranslated Region of Hepatitis A Virus: Update from Clinical Isolates Associated with Mild and Severe Hepatitis
... a 5 ⬘ untranslated region (5 ⬘ UTR), a single open reading frame that encodes both structural and nonstructural proteins, and a 3 ⬘ UTR with a short poly(A) ...
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A preferred region for recombinational patch repair in the 5' untranslated region of primer binding site-impaired murine leukemia virus vectors.
... by 5 to 6 orders of magnitude compared with that of the wild-type ...the region between the neo gene and the mutated primer binding site to allow correct second-strand transfer in reverse ...the 5 * ...
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Comparative performance evaluation of hepatitis C virus genotyping based on the 5' untranslated region versus partial sequencing of the NS5B region of brazilian patients with chronic hepatitis C
... the 5’ untranslated region. Currently, 5’UTR based assays are reasonably accurate with more than 95% concordance with genotypes that have been identified by nucleotide sequencing of the NS5B ...
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The Pseudoknot Region of the 5′ Untranslated Region Is a Determinant of Viral Tropism and Virulence of Foot-and-Mouth Disease Virus
... FMDV 5= untranslated region (UTR) plays an important role during FMDV ...The 5= UTR is ⬎ 1,300 bp long and contains a short segment known as the S fragment, which follows the poly(C) tract, ...
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Prevalence of thymidylate synthase gene 5'-untranslated region variants in an Argentinean sample.
... The mRNA expression of the TYMS gene is thought to be affected by a 28-bp tandem repeat polymorphism within its 5'-untranslated region (UTR; Kaneda et al., 1987). The majority of human TYMS alleles ...
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Dimerization and Template Switching in the 5′ Untranslated Region between Various Subtypes of Human Immunodeficiency Virus Type 1
... the region of homology can be divided into regions of identity ...each region of identity is shown for D to B, C2 to AC, and B to AC in Table ...each region, and this value is illustrated in Fig. 5B ...
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Suppression of a Nuclear aep2 Mutation in Saccharomyces cerevisiae by a Base Substitution in the 5′-Untranslated Region of the Mitochondrial oli1 Gene Encoding Subunit 9 of ATP Synthase
... oli1 region in mtDNA of rho 2 strains retaining mitochondrion-encoded sup- ...oli1 region (not drawn to ...OL-1(15) region in mtDNA of MP3-8C (from which strains analyzed in tester ...S510-3; ...
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The non-primate hepacivirus 5 ' untranslated region possesses internal ribosomal entry site activity
... entire 5 9 UTR and 30 nt of core coding sequence, and another that excluded the initial ...(gt1b) 5 9 UTR, was kindly provided by Kensuka Hirasawa (Licursi et ...NPHV 5 9 UTR amplicons were cloned ...
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A 5' proximal Stem loop Structure of 5' Untranslated Region of Porcine Reproductive and Respiratory Syndrome Virus Genome Is Key for Virus Replication
... the 5’ UTR probably has no function ...the 5 ’ -proximal genomic ends, SL2 may exert regulatory function via interaction with the 3’ -end via RNA-RNA, or RNA-protein-protein-RNA ...
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Aminoglycoside Cross-Resistance in Mycobacterium tuberculosis Due to Mutations in the 5′ Untranslated Region of whiB7
... Mutations in the 5= UTR of whiB7 cause enhanced whiB7 expression and low-level KAN resistance. Based on the location of the whiB7 mutations, we hypothesized that these mutations could affect whiB7 expression. ...
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A nuclear factor binding domain in the 5' untranslated region of the amyloid precursor protein promoter: Implications for the regulation of gene expression
... the 5 ’ - APP -UTR in post-tran- scriptional gene regulation ...the 5’-APP- UTR described ...the 5 ’ - APP -UTR and therefore outside of the DAPB binding ...the 5 ’ - APP -UTR that functions ...
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The 5′ Untranslated Region of Human Bocavirus Capsid Transcripts Regulates Viral mRNA Biogenesis and Alternative Translation
... The 5= UTR with (pBi-R6-VP1u, pBi-R7-VP1u, and pBi-R8-VP1u) or without (pBi-R6, pBi-R7, and pBi-R8) the VP1u sequence was inserted into this vector between the two fluores- cent protein ORFs to verify whether any ...
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Role of the 5′-Proximal Stem-Loop Structure of the 5′ Untranslated Region in Replication and Translation of Hepatitis C Virus RNA
... the 5⬘UTR has multiple important roles in the regulation of viral RNA trans- lation and/or replication (3, 4, 10, 18, 19, 22, 45, ...the 5⬘ end of the viral RNA genome controls both viral RNA translation ...
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Roles of the 5′ Untranslated Region of Nonprimate Hepacivirus in Translation Initiation and Viral Replication
... EHcV 5= UTR exhibited IRES activity ...EHcV 5= UTR were functionally substituted for domains II and III-IV of the HCV 5= UTR, respectively, in the HCV 5= UTR ...EHcV 5= UTRs exhibited ...
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Comparative analysis of hepatitis C virus phylogenies from coding and non coding regions: the 5' untranslated region (UTR) fails to classify subtypes
... the 5' UTR, though only a small portion of this region is ampli- fied for ..."Okamoto region" (from nt 8282 to 8610 in the H77 reference genome) for its ability to represent the phylog- eny ...
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Translation efficiency of adenovirus early region 1A mRNAs deleted in the 5' untranslated region.
... In this study, we used these deletion mutants to determine the effects of the 5' sequence on translational efficiency, examining both EIA mRNA levels and protein levels in the same infec[r] ...
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Cap-independent translation by the 5' untranslated region of Theiler's murine encephalomyelitis virus.
... Comparison of the Cat and Luc activities expressed by the various bicistronic mRNAs both in transfected cells and in in vitro translation reactions strongly suggests that the TMEV 5'UTR [r] ...
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Influence of Theiler's murine encephalomyelitis virus 5' untranslated region on translation and neurovirulence.
... Our previous results from chimeric cDNA studies had indicated that GDVII 1B-2C has a major role in determining neurovirulence but that the addition of GDVII sequences 5' to this also con[r] ...
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